DOK4

Gene Symbol DOK4
Entrez Gene 55715
Alt Symbol -
Species Human
Gene Type protein-coding
Description docking protein 4
Other Description IRS-5|IRS5|downstream of tyrosine kinase 4|insulin receptor substrate 5
Swissprots Q9BTP2 Q9NVV3 O75209 Q8TEW6
Accessions AAC24310 EAW82932 EAW82933 EAW82934 Q8TEW6 AF466369 AAL74195 AK001350 BAA91642 AK307270 AK315426 BAG37814 AW163719 BC001540 AAH01540 BC003541 AAH03541 DQ893008 ABM83934 DQ896254 ABM87253 XM_005256042 XP_005256099 XM_005256043 XP_005256100 XM_011523226 XP_011521528 NM_018110 NP_060580
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. {ECO:0000250}.
Tissue Specificity Widely expressed. High expression in skeletal muscle, heart, kidney and liver. Weaker expression in spleen, lung and small intestine, brain, heart and. Expressed in both resting and activated peripheral blood T-cells. {ECO:0000269|PubMed:12595900, ECO:0000269|PubMed:12730241}.

Dok-4 CRISPR/Cas9 KO Plasmid (h) - sc-407814 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-4 HDR Plasmid (h) - sc-407814-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-4 Double Nickase Plasmid (h) - sc-407814-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-4 Double Nickase Plasmid (h2) - sc-407814-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-4 CRISPR Activation Plasmid (h) - sc-407814-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-4 CRISPR Activation Plasmid (h2) - sc-407814-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-4 Lentiviral Activation Particles (h) - sc-407814-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-4 Lentiviral Activation Particles (h2) - sc-407814-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-4 siRNA (h) - sc-105313 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dok-4 shRNA Plasmid (h) - sc-105313-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dok-4 shRNA (h) Lentiviral Particles - sc-105313-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DOK4 RNAi - H00055715-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU052431 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7430 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7430 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DOK4 siRNA (Human) - CRJ0856 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DOK4 - MBS829632 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DOK4 (NM_018110.3) - SHH280305 from Creative biogene

Category siRNA
Species Reactivities Human

Human DOK4 siRNA - orb271357 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DOK4 shRNA Plasmid (Human) - CHJ0856 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DOK4 miRNA 3'UTR clone - MiUTR3H-09923 from Creative biogene

Species Reactivities Human
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