Gene Symbol | NAGS |
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Entrez Gene | 162417 |
Alt Symbol | AGAS, ARGA |
Species | Human |
Gene Type | protein-coding |
Description | N-acetylglutamate synthase |
Other Description | N-acetylglutamate synthase, mitochondrial|amino-acid acetyltransferase |
Swissprots | Q8N159 Q8IWR4 B2RAZ9 |
Accessions | AAM75385 EAW51643 Q8N159 AI241153 AK074407 AK091938 AK300923 BAG62555 AK314432 BAG37046 AY116538 AAM75386 AY158070 AAN76451 BC111713 AAI11714 BF589712 XM_011524438 XP_011522740 XM_011524439 XP_011522741 NM_153006 NP_694551 |
Function | Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPSI) activity. |
Subcellular Location | Mitochondrion matrix. |
Tissue Specificity | Highly expressed in the adult liver, kidney and small intestine. Weakly expressed in the fetal liver, lung, pancreas, placenta, heart and brain tissue. {ECO:0000269|PubMed:12459178, ECO:0000269|PubMed:12754705}. |
Top Pathways | Arginine and proline metabolism, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism |
NAGS (Q-12) - sc-132384 from Santa Cruz Biotechnology
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NAGS (H-116) - sc-366676 from Santa Cruz Biotechnology
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NAGS (L-17) - sc-102033 from Santa Cruz Biotechnology
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Anti-NAGS antibody - C-terminal - ab194551 from Abcam
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Anti-NAGS Antibody (aa441-490) - LS-C82850 from LifeSpan Bioscience
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Anti-NAGS Antibody - LS-C332646 from LifeSpan Bioscience
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NAGS Antibody - NBP1-79444 from Novus Biologicals
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NAGS Antibody - H00162417-A01 from Novus Biologicals
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Anti-NAGS antibody produced in rabbit - AV51183 from Sigma-Aldrich
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NAGS antibody - C-terminal region (ARP51183_T100) - ARP51183_T100 from Aviva Systems Biology
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NAGS antibody [N3C3-2] - GTX110466 from GeneTex
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NAGS antibody - 70R-1562 from Fitzgerald
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NAGS Polyclonal Antibody - A3555 from ABclonal
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NAGS antibody - 70R-18743 from Fitzgerald
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NAGS Antibody - abx002567 from Abbexa
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NAGS antibody - 21566-1-AP from Acris Antibodies
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NAGS antibody - H00162417-A01 from Acris Antibodies
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Anti-NAGS, Polyclonal Antibody - 25-A3555 from ARP American Research Products
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NAGS Antibody - 30-708 from ProSci
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Anti-NAGS antibody - STJ24677 from St John's Laboratory Ltd
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NAGS antibody - 21566-1-AP from Proteintech Group
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NAGS - A3555 from NeoScientific
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NAGS Antibody - GWB-MS157D from Genway Biotech
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Anti-NAGS (aa 435-532) polyclonal antibody - DPAB-DC709 from Creative Diagnostics
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Anti-NAGS (aa 434-483) polyclonal antibody - DPABH-17017 from Creative Diagnostics
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