CHGA

Gene Symbol CHGA
Entrez Gene 1113
Alt Symbol CGA
Species Human
Gene Type protein-coding
Description chromogranin A
Other Description SP-I|betagranin (N-terminal fragment of chromogranin A)|catestatin|chromofungin|chromogranin-A|parathyroid secretory protein 1|pituitary secretory protein I
Swissprots B2R9E9 Q9BQB5 Q6NR84 Q96E84 Q53FA8 Q96GL7 P10645
Accessions AAB53685 EAW81505 EAW81506 P10645 AK223381 BAD97101 AK313757 BAG36496 BC001059 AAH01059 BC006459 AAH06459 BC009384 AAH09384 BC012755 AAH12755 BT006869 AAP35515 BX248263 CAD62591 DA201149 DQ891820 ABM82746 DQ895007 ABM85933 J03483 AAA52017 J03915 AAA52018 XM_011536370 XP_011534672 XM_011546640 XP_011544942 NM_001275 NP_001266 NM_001301690 NP_001288619
Function Serpinin: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation. {ECO:0000250|UniProtKB:P26339}.
Subcellular Location Cytoplasmic vesicle, secretory vesicle lumen {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}. Secreted. Note=Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions. {ECO:0000250}.
Tissue Specificity GE-25 is found in the brain. {ECO:0000269|PubMed:7535395}.

Chr-A CRISPR/Cas9 KO Plasmid (h) - sc-400405 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chr-A HDR Plasmid (h) - sc-400405-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chr-A Double Nickase Plasmid (h) - sc-400405-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chr-A Double Nickase Plasmid (h2) - sc-400405-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chr-A CRISPR Activation Plasmid (h) - sc-400405-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chr-A CRISPR Activation Plasmid (h2) - sc-400405-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chr-A Lentiviral Activation Particles (h) - sc-400405-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chr-A Lentiviral Activation Particles (h2) - sc-400405-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Chr-A siRNA (h) - sc-37212 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Chr-A shRNA Plasmid (h) - sc-37212-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Chr-A shRNA (h) Lentiviral Particles - sc-37212-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN6053 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6053 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CHGA siRNA (Human) - CRH0794 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Chromogranin A RNAi - H00001113-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CHGA - MBS8216240 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CHGA (NM_001275.3) - SHH262997 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CHGA(NM_001275.3) - SHG172507 from Creative biogene

Category siRNA
Species Reactivities Human

Human CHGA siRNA - orb261296 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHGA shRNA Plasmid (Human) - CHH0794 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CHGA miRNA 3'UTR clone - MiUTR1H-02115 from Creative biogene

Species Reactivities Human
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