CHGA

Gene Symbol CHGA
Entrez Gene 1113
Alt Symbol CGA
Species Human
Gene Type protein-coding
Description chromogranin A
Other Description SP-I|betagranin (N-terminal fragment of chromogranin A)|catestatin|chromofungin|chromogranin-A|parathyroid secretory protein 1|pituitary secretory protein I
Swissprots B2R9E9 Q9BQB5 Q6NR84 Q96E84 Q53FA8 Q96GL7 P10645
Accessions AAB53685 EAW81505 EAW81506 P10645 AK223381 BAD97101 AK313757 BAG36496 BC001059 AAH01059 BC006459 AAH06459 BC009384 AAH09384 BC012755 AAH12755 BT006869 AAP35515 BX248263 CAD62591 DA201149 DQ891820 ABM82746 DQ895007 ABM85933 J03483 AAA52017 J03915 AAA52018 XM_011536370 XP_011534672 XM_011546640 XP_011544942 NM_001275 NP_001266 NM_001301690 NP_001288619
Function Serpinin: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation. {ECO:0000250|UniProtKB:P26339}.
Subcellular Location Cytoplasmic vesicle, secretory vesicle lumen {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}. Secreted. Note=Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions. {ECO:0000250}.
Tissue Specificity GE-25 is found in the brain. {ECO:0000269|PubMed:7535395}.

Chr-A (C-20) - sc-1488 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Chr-A (C-20): sc-1488. Western blot analysis of chromogranin A isolated from bovine adrenal medulla.

Chr-A (C-12) - sc-393941 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Chr-A (C-12): sc-393941. Western blot analysis of Chr-A expression in non-transfected 293T: sc-117752 (A), human Chr-A transfected 293T: sc-159285 (B) and SH-SY5Y (C) whole cell lysates.

Chr-A (F-12) - sc-376827 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Chr-A (F-12): sc-376827. Western blot analysis of Chr-A expression in non-transfected: sc-117752 (A) and human Chr-A transfected: sc-159285 (B) 293T whole cell lysates.

Chr-A (F-8) - sc-376813 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Chr-A (F-8): sc-376813. Western blot analysis of Chr-A expression in non-transfected: sc-117752 (A) and human Chr-A transfected: sc-159285 (B) 293T whole cell lysates.

Chr-A (E-20) - sc-18232 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Chr-A (E-20): sc-18232. Western blot analysis of human recombinant Chr-A fusion protein.

Chr-A (H-300) - sc-13090 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Chr-A (H-300): sc-13090. Western blot analysis of Chr-A expression in nocodazole-treated SH-SY5Y whole cell lysate.

Chr-A (E-5) - sc-271738 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Chr-A (E-5): sc-271738. Western blot analysis of Chr-A expression in non-transfected: sc-117752 (A) and human Chr-A transfected: sc-159513 (B) 293T whole cell lysates.

Chr-A (I-16) - sc-23556 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Chr-A (I-16): sc-23556. Western blot analysis of purified bovine Chr-A.

Chr-A (PHE5) - sc-53013 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Chr-A (PHE5): sc-53013. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing weak cytoplasmic staining of exocrine glandular cells and cytoplasmic staining of Islets of Langerhans.

Chr-A (LK2H10) - sc-47714 from Santa Cruz Biotechnology

Prices $279.00
Sizes 500 µl ascites
Host Mouse
Clonality Monoclonal
Chr-A (LK2H10): sc-47714. Western blot analysis of Chr-A expression in SHP-77 (A), Hep G2 (B) and SK-N-SH (C) whole cell lysates.

Anti-Chromogranin A antibody - ab15160 from Abcam

Prices $400.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal
ab15160 at 1/250 staining human pancreas tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step was performed before incubation with the antibody for 30 minutes at 25°C. An HRP conjugated rabbit polyclonal was used as the secondary.See Abreview

Anti-Chromogranin A antibody - ab45179 from Abcam

Prices $398.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Chromogranin A antibody (ab45179) at 1/10000 dilution (unpurified) + PC-12 cell lysate at 10 µgSecondaryHRP-conjugated goat anti-rabbit IgG at 1/2000 dilutionObserved band size : 86 kDa (why is the actual band size different from the predicted?)

Anti-Chromogranin A antibody - ab17064 from Abcam

Prices $378.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
Standard Curve for Chromogranin A (Analyte: ab85486) dilution range 1pg/ml to 1ug/ml using Capture Antibody Mouse monoclonal [23A1] to Chromogranin A (ab36997) at 1ug/ml and Detector Antibody Rabbit polyclonal to Chromogranin A (ab17064) at 0.5ug/ml. Concentration of ab17064 may vary from lot to lot; please use this curve as guideline.

Anti-Chromogranin A antibody - ab109993 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-Chromogranin A antibody (ab109993) at 0.1 µg/ml + Human kidney lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-Chromogranin A antibody - ab61967 from Abcam

Prices $370.00
Sizes 100 µl
Host Chicken
Clonality Polyclonal

Anti-Chromogranin A antibody [1A6B6] - ab166701 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A6B6
All lanes : Anti-Chromogranin A antibody [1A6B6] (ab166701) at 1/500 dilutionLane 1 : MOLT4 cell lysateLane 2 : SK-N-SH cell lysateLane 3 : HepG2 cell lysateLane 4 : PC12 cell lysate

Anti-Chromogranin A antibody [23A1] - ab36997 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 23A1
Standard Curve for Chromogranin A (Analyte: ab85486) dilution range 1pg/ml to 1ug/ml using Capture Antibody Mouse monoclonal [23A1] to Chromogranin A (ab36997) at 1ug/ml and Detector Antibody Rabbit polyclonal to Chromogranin A (ab17064) at 0.5ug/ml. Concentration of ab17064 may vary from lot to lot; please use this curve as guideline.

Anti-Chromogranin A antibody [3A5] - ab81606 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A5
All lanes : Anti-Chromogranin A antibody [3A5] (ab81606) at 1/500 dilutionLane 1 : Cell lysates of A549Lane 2 : Cell lysates of 293TLysates/proteins at 35 µg per lane.SecondaryGoat anti-mouse secondary antibody conjugated to HRP developed using the ECL technique

Anti-Chromogranin A antibody [CGA414] - ab187368 from Abcam

Prices $379.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone CGA414
Immunohistochemical analysis of paraffin-embedded formalin fixed pancreas tissue labeling Chromogranin A with ab187368 at 1 µg/µl.

Anti-Chromogranin A antibody [EP1030Y] - ab68271 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1030Y
Anti-Chromogranin A antibody [EP1030Y] (ab68271) + SH-SY5Y cell lysate at 10 µgSecondaryHRP conjugated Goat anti-rabbit at 1/2000 dilution

Anti-Chromogranin A antibody [EP1030Y] (HRP) - ab199194 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1030Y
Anti-Chromogranin A antibody [EP1030Y] (HRP) (ab199194) at 1/5000 dilution + SHSY-5Y (Human neuroblastoma cell line) Whole Cell Lysate at 10 µgdeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Chromogranin A antibody [EP1031Y] - ab52983 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1031Y
Anti-Chromogranin A antibody [EP1031Y] (ab52983) at 1/1000000 dilution + PC12 cell lysate at 10 µgSecondarygoat anti-rabbit HRP labelled at 1/2000 dilution

Anti-Chromogranin A antibody [LK2H10] - ab8204 from Abcam

Prices $382.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone LK2H10
ab8204 staining Chromogen A in normal Human colon mucosa tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 1% BSA for 30 minutes at room temperature; antigen retrieval was by heat mediation with citrate buffer. Samples were incubated with primary antibody (1/10 in TBS) for 1 hour. An undiluted HRP-conjugated Goat polyclonal was used as the secondary antibody.See Abreview

Anti-Chromogranin A antibody [LK2H10] - ab80787 from Abcam

Prices $378.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone LK2H10
Formalin-fixed, paraffin-embedded human pancreatic tumor stained with ab80787 at a 1/800 dilution using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.

Anti-Chromogranin A antibody [LK2H10] (Biotin) - ab79276 from Abcam

Prices $370.00
Sizes 250 µl
Host Mouse
Clonality Monoclonal
Clone LK2H10
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