Gene Symbol | CHGA |
---|---|
Entrez Gene | 1113 |
Alt Symbol | CGA |
Species | Human |
Gene Type | protein-coding |
Description | chromogranin A |
Other Description | SP-I|betagranin (N-terminal fragment of chromogranin A)|catestatin|chromofungin|chromogranin-A|parathyroid secretory protein 1|pituitary secretory protein I |
Swissprots | B2R9E9 Q9BQB5 Q6NR84 Q96E84 Q53FA8 Q96GL7 P10645 |
Accessions | AAB53685 EAW81505 EAW81506 P10645 AK223381 BAD97101 AK313757 BAG36496 BC001059 AAH01059 BC006459 AAH06459 BC009384 AAH09384 BC012755 AAH12755 BT006869 AAP35515 BX248263 CAD62591 DA201149 DQ891820 ABM82746 DQ895007 ABM85933 J03483 AAA52017 J03915 AAA52018 XM_011536370 XP_011534672 XM_011546640 XP_011544942 NM_001275 NP_001266 NM_001301690 NP_001288619 |
Function | Serpinin: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation. {ECO:0000250|UniProtKB:P26339}. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle lumen {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}. Secreted. Note=Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions. {ECO:0000250}. |
Tissue Specificity | GE-25 is found in the brain. {ECO:0000269|PubMed:7535395}. |
Chromogranin A peptide - ab138920 from Abcam
|
||||||||
Chromogranin A peptide - ab93753 from Abcam
|
||||||||
Human Chromogranin A full length protein - ab85486 from Abcam
|
||||||||
Human Chromogranin A peptide - ab50460 from Abcam
|
||||||||
Human Chromogranin A protein fragment - ab38256 from Abcam
|
||||||||
Human Chromogranin A protein fragment - ab85339 from Abcam
|
||||||||
CHGA / Chromogranin A Antibody Blocking Peptide - LS-E1216 from LifeSpan Bioscience
|
||||||||
CHGA / Chromogranin A Antibody Blocking Peptide - LS-E26109 from LifeSpan Bioscience
|
||||||||
CHGA / Chromogranin A Antibody Blocking Peptide - LS-E15437 from LifeSpan Bioscience
|
||||||||
Chromogranin A Partial Recombinant Protein - H00001113-Q01 from Novus Biologicals
|
||||||||
Recombinant Human Chromogranin A Protein - NBC1-26369 from Novus Biologicals
|
||||||||
Chromogranin A Recombinant Protein - H00001113-P01 from Novus Biologicals
|
||||||||
CHGA-Antibody-Center-Blocking-peptide - BP10165c from Abgent, a WuXi AppTec company
|
||||||||
CMGA-Antibody-C-term-Blocking-peptide - BP11784b from Abgent, a WuXi AppTec company
|
||||||||
CHGA-Antibody-Center-Blocking-Peptide - BP14938c from Abgent, a WuXi AppTec company
|
||||||||
Chromogranin-A-324-337-human - SP3246b from Abgent, a WuXi AppTec company
|
||||||||
Chromogranin-A-324-337-human - SP3246a from Abgent, a WuXi AppTec company
|
||||||||
Recombinant human Chromogranin-A (OPCA00050) - OPCA00050 from Aviva Systems Biology
|
||||||||
Recombinant human Chromogranin-A (OPCA01223) - OPCA01223 from Aviva Systems Biology
|
||||||||
CHGA Protein (OPPA01385) - OPPA01385 from Aviva Systems Biology
|
||||||||
CHGA Protein (OPPA02120) - OPPA02120 from Aviva Systems Biology
|
||||||||
CHGA Protein (OPPA02155) - OPPA02155 from Aviva Systems Biology
|
||||||||
Human CHGA protein - orb245790 from Biorbyt
|
||||||||
Human CHGA protein - orb81027 from Biorbyt
|
||||||||
Human CHGA protein - orb244108 from Biorbyt
|