Gene Symbol | RAB22A |
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Entrez Gene | 57403 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RAB22A, member RAS oncogene family |
Other Description | GTP-binding protein RAB22A|rab-22|ras-related protein Rab-22A |
Swissprots | E1P605 B3KR86 Q8TF12 Q9H4E6 Q9UL26 |
Accessions | EAW75496 EAW75497 Q9UL26 AF091034 AAF00047 AJ276210 CAC10538 AK054767 AK091180 BAG52298 BC007036 AAH07036 BC015710 AAH15710 BC016864 BC042545 BC063457 AAH63457 BI457862 BT007046 AAP35695 DB452461 NM_020673 NP_065724 |
Function | Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form. {ECO:0000269|PubMed:16537905, ECO:0000269|PubMed:21849477}. |
Subcellular Location | Endosome membrane {ECO:0000250}; Lipid- anchor {ECO:0000250}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Early endosome. Cell projection, ruffle. Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis. |
Top Pathways | Endocytosis |
Rab 22A (C-17) - sc-98097 from Santa Cruz Biotechnology
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Rab 22A (G-7) - sc-390726 from Santa Cruz Biotechnology
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Rab 22A (H-42) - sc-366602 from Santa Cruz Biotechnology
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Rab 22A (W-15) - sc-98099 from Santa Cruz Biotechnology
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Anti-RAB22A antibody - ab170061 from Abcam
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Anti-RAB22A antibody - ab99205 from Abcam
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Anti-RAB22A antibody - ab67049 from Abcam
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Anti-RAB22A antibody [EPR9486] - ab137093 from Abcam
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Anti-RAB22A antibody [EPR9487] - ab138505 from Abcam
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Anti-RAB22A antibody - C-terminal - ab138635 from Abcam
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Anti-RAB22A / RAB22 Antibody (aa166-192, AP) - LS-C223807 from LifeSpan Bioscience
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Anti-RAB22A / RAB22 Antibody (aa166-192, APC) - LS-C223809 from LifeSpan Bioscience
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Anti-RAB22A / RAB22 Antibody (C-Terminus) - LS-C112063 from LifeSpan Bioscience
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Anti-RAB22A / RAB22 Antibody (aa166-192, Biotin) - LS-C223810 from LifeSpan Bioscience
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Anti-RAB22A / RAB22 Antibody (aa166-192, Azide-free, HRP) - LS-C223811 from LifeSpan Bioscience
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Anti-RAB22A / RAB22 Antibody (aa166-192, FITC) - LS-C223812 from LifeSpan Bioscience
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Anti-RAB22A / RAB22 Antibody (aa166-192, PE) - LS-C223813 from LifeSpan Bioscience
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Anti-RAB22A / RAB22 Antibody (aa165-192) - LS-C324466 from LifeSpan Bioscience
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Anti-RAB22A / RAB22 Antibody (aa166-192) - LS-C158783 from LifeSpan Bioscience
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RAB22A Antibody - 21740002 from Novus Biologicals
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RAB22A Antibody - NBP2-39080 from Novus Biologicals
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RAB22A Antibody - H00057403-B01P from Novus Biologicals
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RAB22A Antibody - H00057403-B01 from Novus Biologicals
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RAB22A Antibody (2B12) - H00057403-M03 from Novus Biologicals
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RAB22A Antibody - H00057403-D01 from Novus Biologicals
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