Gene Symbol | RAB22A |
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Entrez Gene | 57403 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | RAB22A, member RAS oncogene family |
Other Description | GTP-binding protein RAB22A|rab-22|ras-related protein Rab-22A |
Swissprots | E1P605 B3KR86 Q8TF12 Q9H4E6 Q9UL26 |
Accessions | EAW75496 EAW75497 Q9UL26 AF091034 AAF00047 AJ276210 CAC10538 AK054767 AK091180 BAG52298 BC007036 AAH07036 BC015710 AAH15710 BC016864 BC042545 BC063457 AAH63457 BI457862 BT007046 AAP35695 DB452461 NM_020673 NP_065724 |
Function | Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form. {ECO:0000269|PubMed:16537905, ECO:0000269|PubMed:21849477}. |
Subcellular Location | Endosome membrane {ECO:0000250}; Lipid- anchor {ECO:0000250}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Early endosome. Cell projection, ruffle. Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis. |
Top Pathways | Endocytosis |
Active human RAB22A full length protein - ab90109 from Abcam
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RAB22A / RAB22 Antibody Blocking Peptide - LS-E6221 from LifeSpan Bioscience
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RAB22A / RAB22 Antibody Blocking Peptide - LS-E20970 from LifeSpan Bioscience
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RAB22A Recombinant Protein - H00057403-P01 from Novus Biologicals
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Recombinant Human RAB22A Protein - NBP1-72452 from Novus Biologicals
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RAB22A-Antibody-C-term-Blocking-Peptide - BP18867b from Abgent, a WuXi AppTec company
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Human RAB22A protein - orb169137 from Biorbyt
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RAB22A Blocking Peptide - 33R-3964 from Fitzgerald
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RAB22A protein (His tag) - 80R-1966 from Fitzgerald
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RAB22A / RAB22 (1-194, His-tag) - AR39152PU-N from Acris Antibodies
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RAB22A / RAB22 (1-194, His-tag) - AR39152PU-S from Acris Antibodies
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RAB22A / RAB22 - H00057403-P01-02 from Acris Antibodies
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RAB22A, 1-194aa, Human, His tag, E.coli - 01-RAB-22A from ARP American Research Products
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RAB22A fusion protein - ag2769 from Proteintech Group
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RAB22A Human - PRPS-936 from NeoScientific
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RAB22A, 1-194aa, Recombinant Protein - GWB-P0828I from Genway Biotech
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Recombinant Human RAB22A, Member RAS Oncogene Family, GST-tagged - RAB22A-1101H from Creative Biomart
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Recombinant Human RAB22A, His-tagged - RAB22A-30801TH from Creative Biomart
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Recombinant Human RAB22A, Member RAS Oncogene Family, His-tagged - RAB22A-6862H from Creative Biomart
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RAB22A 1-194aa - CMB-1043 from Reagent Proteins
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Recombinant Human Ras-related protein Rab-22A(RAB22A) - CSB-YP891957HU CSB-EP891957HU CSB-BP891957HU CSB-MP891957HU from Cusabio
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RAB22A, 1-194aa, Human, His tag, E.coli - ATGP1210 from ATGen
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RAB22A / RAB22 - TP309511 from Acris Antibodies
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RAB22A Recombinant Protein Antigen - NBP2-39080PEP from Novus Biologicals
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RAB22A Peptide, Human - M34GP12832H from Creative Peptides
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