LY96

Gene Symbol	LY96
Entrez Gene	23643
Alt Symbol	ESOP-1, MD-2, MD2, ly-96
Species	Human
Gene Type	protein-coding
Description	lymphocyte antigen 96
Other Description	myeloid differentiation protein-2|protein MD-2
Swissprots	B3Y6A5 E5RJJ7 Q9Y6Y9
Accessions	CBX47650 EAW87024 Q9Y6Y9 AB018549 BAA78717 AB446498 BAG55275 AF168121 AAF89635 BC020690 AAH20690 BG435728 XM_011517508 XP_011515810 NM_001195797 NP_001182726 NM_015364 NP_056179
Function	Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.
Subcellular Location	Secreted, extracellular space.
Top Pathways	Toll-like receptor signaling pathway, Pathogenic Escherichia coli infection, Toxoplasmosis, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MD2 full length protein - ab132303 from Abcam Category Protein Source Wheat germ Species Human

Human MD2 full length protein - ab73936 from Abcam Category Protein Source E. coli Species Human

Human MD2 peptide - ab39815 from Abcam Category Peptide Species Human

MD2 peptide - ab95050 from Abcam Category Peptide

LY96 / MD2 / MD-2 Antibody Blocking Peptide - LS-E5011 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LY96 / MD2 / MD-2 Antibody Blocking Peptide - LS-E22386 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LY96 / MD2 / MD-2 Antibody Blocking Peptide - LS-E30061 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human MD-2 Protein - H00023643-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MD-2 Blocking Peptide - NBP1-77201PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

LY96-Antibody-C-term-Blocking-Peptide - BP17412b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MD2 Peptide - GTX85517-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Recombinant Human MD-2 - 1787-MD-050 from R&D Systems Category Protein Source E. coli-derived

Recombinant Human MD-2, CF - 1787-MD-050/CF from R&D Systems Category Protein Source E. coli-derived

LY96 Blocking Peptide - 33R-6768 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Lymphocyte Antigen 96 Protein - abx067843 from Abbexa Category Protein Source E.coli Species Human

MD-2 - H00023643-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MD-2 - H00023643-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MD-2 Control Peptide - AP30552CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Lymphocyte Antigen 96 (LY96), Human - 20-9294 from ARP American Research Products Category Protein Prices $449.00 Sizes 50 µg Source E.coli Species Human

MD-2 Peptide - 3289P from ProSci Category Peptide Species Human

MD-2 Recombinant Protein - 95-108 from ProSci Category Protein Prices $215.00 Sizes 50 µg Source E. coli Species Human

LY96 fusion protein - ag2447 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human LY96 protein, MYC/DDK-tagged - LY96-327H from Creative Biomart Category Protein Source HEK293 cells Species Human

Recombinant Human LY96, GST-tagged - LY96-154H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human LY96 - LY96-445H from Creative Biomart Category Protein Source E. coli Species Human

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