LY96

Gene Symbol	LY96
Entrez Gene	23643
Alt Symbol	ESOP-1, MD-2, MD2, ly-96
Species	Human
Gene Type	protein-coding
Description	lymphocyte antigen 96
Other Description	myeloid differentiation protein-2|protein MD-2
Swissprots	B3Y6A5 E5RJJ7 Q9Y6Y9
Accessions	CBX47650 EAW87024 Q9Y6Y9 AB018549 BAA78717 AB446498 BAG55275 AF168121 AAF89635 BC020690 AAH20690 BG435728 XM_011517508 XP_011515810 NM_001195797 NP_001182726 NM_015364 NP_056179
Function	Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both MD2 and TLR4, but not TLR4 alone, respond to LPS.
Subcellular Location	Secreted, extracellular space.
Top Pathways	Toll-like receptor signaling pathway, Pathogenic Escherichia coli infection, Toxoplasmosis, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MD-2 CRISPR/Cas9 KO Plasmid (h) - sc-417315 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MD-2 HDR Plasmid (h) - sc-417315-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MD-2 Double Nickase Plasmid (h) - sc-417315-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MD-2 Double Nickase Plasmid (h2) - sc-417315-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MD-2 CRISPR Activation Plasmid (h) - sc-417315-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MD-2 CRISPR Activation Plasmid (h2) - sc-417315-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MD-2 Lentiviral Activation Particles (h) - sc-417315-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MD-2 Lentiviral Activation Particles (h2) - sc-417315-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MD-2 siRNA (h) - sc-35889 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MD-2 shRNA Plasmid (h) - sc-35889-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MD-2 shRNA (h) Lentiviral Particles - sc-35889-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU056931 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12847 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12847 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

LY96 siRNA (Human) - CRH8417 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

MD-2 RNAi - H00023643-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

shRNA set against Human LY96 (NM_015364.4) - SHH335931 from Creative biogene Category siRNA Species Reactivities Human

Human LY96 siRNA - orb268919 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

LY96 shRNA Plasmid (Human) - CHH8417 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

LY96 miRNA 3'UTR clone - MiUTR4H-TG05233 from Creative biogene Species Reactivities Human

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