Gene Symbol | MYLK3 |
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Entrez Gene | 91807 |
Alt Symbol | MLCK, MLCK2, caMLCK |
Species | Human |
Gene Type | protein-coding |
Description | myosin light chain kinase 3 |
Other Description | MLC kinase|cardiac-MLCK|cardiac-MyBP-C associated Ca/CaM kinase|cardiac-MyBP-C-associated Ca/CaM kinase|putative myosin light chain kinase 3 |
Swissprots | Q96DV1 B7Z5U8 Q32MK0 Q32MK1 B5BUL9 |
Accessions | CCQ43924 EAW82687 Q32MK0 AB451455 BAG70269 AJ247087 CAC42766 AK299443 BAH13034 AL691746 BC039103 BC109096 BC109097 AAI09098 CR739116 DA561361 HG508011 XM_005256233 XP_005256290 XM_005256234 XP_005256291 XM_005256235 XP_005256292 XM_006721334 XP_006721397 XM_011523448 XP_011521750 XR_933482 NM_001308301 NP_001295230 NM_182493 NP_872299 |
Function | Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Restricted to heart. {ECO:0000269|PubMed:17885681}. |
Top Pathways | Focal adhesion, Calcium signaling pathway, Vascular smooth muscle contraction, Gastric acid secretion, Oxytocin signaling pathway |
MYLK3 (P-16) - sc-165056 from Santa Cruz Biotechnology
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MYLK3 (S-18) - sc-165057 from Santa Cruz Biotechnology
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Anti-MYLK3 antibody - ab71826 from Abcam
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Anti-MYLK3 antibody - ab122643 from Abcam
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Anti-MYLK3 antibody - C-terminal - ab177358 from Abcam
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Anti-MYLK3 antibody - N-terminal - ab199158 from Abcam
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Anti-MYLK3 Antibody (aa535-562, APC) - LS-C237868 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa535-562, AP) - LS-C237867 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa535-562, FITC) - LS-C237871 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa535-562, Biotin) - LS-C237869 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa535-562, PE) - LS-C237872 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa173-203, APC) - LS-C237874 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa535-562) - LS-C164709 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa173-203, AP) - LS-C237873 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa173-203, FITC) - LS-C237875 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa173-203, PE) - LS-C237877 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (N-Terminus, AP) - LS-C245095 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (N-Terminus, FITC) - LS-C245097 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (N-Terminus, APC) - LS-C245096 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa173-203, Azide-free, HRP) - LS-C248872 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa173-203, Biotin) - LS-C237876 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (N-Terminus, PE) - LS-C245103 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa535-562, Azide-free, HRP) - LS-C248870 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (N-Terminus, Azide-free, HRP) - LS-C247715 from LifeSpan Bioscience
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Anti-MYLK3 Antibody (aa174-203) - LS-C164492 from LifeSpan Bioscience
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