| Gene Symbol |
MYLK3
|
| Entrez Gene |
91807
|
| Alt Symbol |
MLCK, MLCK2, caMLCK
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myosin light chain kinase 3
|
| Other Description |
MLC kinase|cardiac-MLCK|cardiac-MyBP-C associated Ca/CaM kinase|cardiac-MyBP-C-associated Ca/CaM kinase|putative myosin light chain kinase 3
|
| Swissprots |
Q96DV1 B7Z5U8 Q32MK0 Q32MK1 B5BUL9
|
| Accessions |
CCQ43924 EAW82687 Q32MK0 AB451455 BAG70269 AJ247087 CAC42766 AK299443 BAH13034 AL691746 BC039103 BC109096 BC109097 AAI09098 CR739116 DA561361 HG508011 XM_005256233 XP_005256290 XM_005256234 XP_005256291 XM_005256235 XP_005256292 XM_006721334 XP_006721397 XM_011523448 XP_011521750 XR_933482 NM_001308301 NP_001295230 NM_182493 NP_872299
|
| Function |
Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Restricted to heart. {ECO:0000269|PubMed:17885681}.
|
| Top Pathways |
Focal adhesion, Calcium signaling pathway, Vascular smooth muscle contraction, Gastric acid secretion, Oxytocin signaling pathway
|