Gene Symbol | MYLK3 |
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Entrez Gene | 91807 |
Alt Symbol | MLCK, MLCK2, caMLCK |
Species | Human |
Gene Type | protein-coding |
Description | myosin light chain kinase 3 |
Other Description | MLC kinase|cardiac-MLCK|cardiac-MyBP-C associated Ca/CaM kinase|cardiac-MyBP-C-associated Ca/CaM kinase|putative myosin light chain kinase 3 |
Swissprots | Q96DV1 B7Z5U8 Q32MK0 Q32MK1 B5BUL9 |
Accessions | CCQ43924 EAW82687 Q32MK0 AB451455 BAG70269 AJ247087 CAC42766 AK299443 BAH13034 AL691746 BC039103 BC109096 BC109097 AAI09098 CR739116 DA561361 HG508011 XM_005256233 XP_005256290 XM_005256234 XP_005256291 XM_005256235 XP_005256292 XM_006721334 XP_006721397 XM_011523448 XP_011521750 XR_933482 NM_001308301 NP_001295230 NM_182493 NP_872299 |
Function | Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Restricted to heart. {ECO:0000269|PubMed:17885681}. |
Top Pathways | Focal adhesion, Calcium signaling pathway, Vascular smooth muscle contraction, Gastric acid secretion, Oxytocin signaling pathway |
Active human MYLK3 full length protein - ab84799 from Abcam
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Human MYLK3 protein fragment - ab164879 from Abcam
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MYLK3 Antibody Blocking Peptide - LS-E1261 from LifeSpan Bioscience
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MYLK3 Antibody Blocking Peptide - LS-E2813 from LifeSpan Bioscience
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MYLK3 Antibody Blocking Peptide - LS-E24789 from LifeSpan Bioscience
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Recombinant Human MYLK3 Protein - H00091807-Q01 from Novus Biologicals
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MYLK3-Antibody-Center-Blocking-peptide - BP11849c from Abgent, a WuXi AppTec company
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MYLK3-Antibody-N-term-Blocking-peptide - BP7965a from Abgent, a WuXi AppTec company
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MLCK - H00091807-Q01-10 from Acris Antibodies
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MLCK - H00091807-Q01-25 from Acris Antibodies
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MYLK3 fusion protein - Ag17370 from Proteintech Group
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MYLK3 fusion protein - Ag16137 from Proteintech Group
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Recombinant Human Myosin Light Chain Kinase 3, GST-tagged, Active - MYLK3-366H from Creative Biomart
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Recombinant Myosin Light Chain Kinase 3 (MYLK3) - RPD429Hu01 from Uscn Life Science Inc.
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Recombinant Myosin Light Chain Kinase 3 (MYLK3) - RPD429Mu01 from Uscn Life Science Inc.
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Recombinant Myosin Light Chain Kinase 3 (MYLK3) - RPD429Hu01 from Cloud-clone
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Recombinant Human Putative myosin light chain kinase 3(MYLK3) ,partial - CSB-YP658362HU CSB-EP658362HU CSB-BP658362HU CSB-MP658362HU from Cusabio
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Myosin Light Chain Kinase 3 Protein (Recombinant) - abx166477 from Abbexa
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MYLK3 Recombinant Protein Antigen - NBP1-86648PEP from Novus Biologicals
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MYLK3 Peptide, Human - M34GP10013H from Creative Peptides
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Recombinant Myosin Light Chain Kinase 3 (MYLK3) - RPU51385 from Biomatik
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MYLK3 Recombinant Protein (OPCD05526) - OPCD05526 from Aviva Systems Biology
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Putative myosin light chain kinase 3 (MYLK3), partial, Recombinant Protein - MBS1297648 from MyBioSource
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