MTPAP

Gene Symbol MTPAP
Entrez Gene 55149
Alt Symbol PAPD1, SPAX4
Species Human
Gene Type protein-coding
Description mitochondrial poly(A) polymerase
Other Description PAP-associated domain-containing protein 1|TUTase 1|poly(A) RNA polymerase, mitochondrial|polynucleotide adenylyltransferase|terminal uridylyltransferase 1
Swissprots D3DRX0 Q6P7E5 Q659E3 Q9NVV4 Q9HA74
Accessions EAW86014 EAW86015 Q9NVV4 AB194709 BAD98252 AK001348 BAA91641 AK022188 BAB13981 AK125211 AY364242 AAQ76801 BC061703 AAH61703 DA086747 NM_018109 NP_060579
Function Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA. {ECO:0000269|PubMed:15547249, ECO:0000269|PubMed:15769737, ECO:0000269|PubMed:18172165, ECO:0000269|PubMed:20970105, ECO:0000269|PubMed:21292163}.
Subcellular Location Cytoplasm. Mitochondrion.
Tissue Specificity Ubiquitous, with stronger expression in tissues with high energy requirements: heart, brain, and skeletal muscle. {ECO:0000269|PubMed:15547249}.

Human Poly(A) RNA polymerase, mitochondrial full length protein - ab162984 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162984 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human PAPD1 Protein - H00055149-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

PAPD1 - H00055149-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

Recombinant Human Poly(A) RNA polymerase, mitochondrial(MTPAP) - CSB-YP882118HU CSB-EP882118HU CSB-BP882118HU CSB-MP882118HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Poly (A) RNA polymerase, mitochondrial (MTPAP), Recombinant Protein - MBS1482524 from MyBioSource

Category Protein
Prices $1,340.00, $1,340.00, $1,555.00, $1,555.00, $2,215.00, $2,215.00, $2,680.00, $2,680.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

PAPD1 Recombinant Protein Antigen - NBP1-83856PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

PAPD1-Antibody-N-term-Blocking-Peptide - BP8847a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

MTPAP Peptide, Human - M34GP09904H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

PAPD1 Recombinant Protein Antigen - NBP2-55422PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human
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