MTPAP

Gene Symbol MTPAP
Entrez Gene 55149
Alt Symbol PAPD1, SPAX4
Species Human
Gene Type protein-coding
Description mitochondrial poly(A) polymerase
Other Description PAP-associated domain-containing protein 1|TUTase 1|poly(A) RNA polymerase, mitochondrial|polynucleotide adenylyltransferase|terminal uridylyltransferase 1
Swissprots D3DRX0 Q6P7E5 Q659E3 Q9NVV4 Q9HA74
Accessions EAW86014 EAW86015 Q9NVV4 AB194709 BAD98252 AK001348 BAA91641 AK022188 BAB13981 AK125211 AY364242 AAQ76801 BC061703 AAH61703 DA086747 NM_018109 NP_060579
Function Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA. {ECO:0000269|PubMed:15547249, ECO:0000269|PubMed:15769737, ECO:0000269|PubMed:18172165, ECO:0000269|PubMed:20970105, ECO:0000269|PubMed:21292163}.
Subcellular Location Cytoplasm. Mitochondrion.
Tissue Specificity Ubiquitous, with stronger expression in tissues with high energy requirements: heart, brain, and skeletal muscle. {ECO:0000269|PubMed:15547249}.

PAPD1 CRISPR/Cas9 KO Plasmid (h) - sc-412459 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD1 HDR Plasmid (h) - sc-412459-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD1 Double Nickase Plasmid (h) - sc-412459-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD1 Double Nickase Plasmid (h2) - sc-412459-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD1 CRISPR Activation Plasmid (h) - sc-412459-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD1 CRISPR Activation Plasmid (h2) - sc-412459-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD1 Lentiviral Activation Particles (h) - sc-412459-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD1 Lentiviral Activation Particles (h2) - sc-412459-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAPD1 siRNA (h) - sc-90573 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAPD1 shRNA Plasmid (h) - sc-90573-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAPD1 shRNA (h) Lentiviral Particles - sc-90573-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAPD1 RNAi - H00055149-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU014891 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14728 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14728 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07028 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07028

MTPAP siRNA (Human) - CRJ0506 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MTPAP (NM_018109.3) - SHH346620 from Creative biogene

Category siRNA
Species Reactivities Human

Human MTPAP siRNA - orb271007 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MTPAP shRNA Plasmid (Human) - CHJ0506 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MTPAP miRNA 3'UTR clone - MiUTR4H-TG05719 from Creative biogene

Species Reactivities Human
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