TERF2

Gene Symbol TERF2
Entrez Gene 7014
Alt Symbol TRBF2, TRF2
Species Human
Gene Type protein-coding
Description telomeric repeat binding factor 2
Other Description TTAGGG repeat-binding factor 2|telomeric DNA-binding protein|telomeric repeat binding protein 2|telomeric repeat-binding factor 2
Swissprots Q15554
Accessions EAW83273 EAW83274 Q15554 AF002999 AAB81135 BC024890 AAH24890 BX090758 CB216181 HY046320 U95970 AAD00821 X93512 CAA63769 XM_005256121 XP_005256178 XM_005256122 XP_005256179 XM_005256123 XP_005256180 XM_005256124 XP_005256181 XM_011523308 XP_011521610 NM_005652 NP_005643
Function Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin complex, TERF2IP/RAP1 and DCLRE1B/Apollo. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Together with DCLRE1B/Apollo, plays a key role in telomeric loop (T loop) formation by generating 3' single- stranded overhang at the leading end telomeres: T loops have been proposed to protect chromosome ends from degradation a
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00625, ECO:0000269|PubMed:20655466}. Chromosome, telomere {ECO:0000269|PubMed:20655466}. Note=Colocalizes with telomeric DNA in interphase cells and is located at chromosome ends during metaphase.
Tissue Specificity Ubiquitous. Highly expressed in spleen, thymus, prostate, uterus, testis, small intestine, colon and peripheral blood leukocytes.

Rabbit anti-TRF2 Antibody, Affinity Purified - PLA0144 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunofluorescence</B>: This antibody is qualified for the Proximity Ligation Assay (PLA). The above image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic F-actin (green), and PLA positive signal (red).

Human TERF2 / TRF2 ELISA Kit (Sandwich ELISA) - LS-F8779 from LifeSpan Bioscience

Category ELISA Kit
Prices $720.00
Sizes 1 plate
Sensitivity 0.063 ng/ml
Range 0.156-10 ng/ml

Telomeric Repeat Binding Factor 2 (TERF2), Human, ELISA Kit - SEF384Hu from ARP American Research Products

Category ELISA Kit
Prices $720.00
Sizes 96 t
Sensitivity 0.061ng/mL
Range 0.156-10ng/mL

Telomeric repeat-binding factor 2 (TERF2), Human, ELISA Kit - CSB-EL023388HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 14 pg/ml
Range 56.25 pg/ml-3600 pg/ml

Telomeric repeat-binding factor 2 (TERF2), Human, ELISA Kit - E01T0676 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Telomeric repeat-binding factor 2 (TERF2), ELISA Kit - MBS7215368 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric repeat-binding factor 2 (TERF2), ELISA Kit - MBS7220245 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric repeat-binding factor 2 (TERF2), ELISA Kit - MBS7242096 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric repeat-binding factor 2 (TERF2), ELISA Kit - MBS7209083 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric repeat-binding factor 2 (TERF2), ELISA Kit - MBS7204739 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric repeat-binding factor 2 (TERF2) , ELISA Kit - MBS901269 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 14 pg/ml
Range 56.25 pg/ml-3600 pg/ml

Telomeric repeat-binding factor 2 (TERF2), ELISA Kit - MBS7217833 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric repeat-binding factor 2 (TERF2), ELISA Kit - MBS7214556 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric repeat-binding factor 2 (TERF2), ELISA Kit - MBS7213808 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric repeat-binding factor 2 (TERF2), ELISA Kit - MBS7229691 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric repeat-binding factor 2 (TERF2), ELISA Kit - MBS7204607 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/mL.

Telomeric Repeat Binding Factor 2, ELISA Kit - MBS083714 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric Repeat Binding Factor 2, ELISA Kit - MBS098053 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric Repeat Binding Factor 2, ELISA Kit - MBS083990 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric Repeat Binding Factor 2, ELISA Kit - MBS056892 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric Repeat Binding Factor 2, ELISA Kit - MBS063046 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric Repeat Binding Factor 2, ELISA Kit - MBS093308 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric Repeat Binding Factor 2, ELISA Kit - MBS068498 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric repeat binding factor 2 (TERF2), ELISA Kit - MBS7214614 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Telomeric Repeat Binding Factor 2 (TERF2), ELISA Kit - MBS2021693 from MyBioSource

Category ELISA Kit
Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.059ng/mL.
Range 0.156-10ng/mL
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