MAFB

Gene Symbol MAFB
Entrez Gene 9935
Alt Symbol KRML, MCTO
Species Human
Gene Type protein-coding
Description v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
Other Description Kreisler maf-related leucine zipper homolog|MAFB/Kreisler basic region/leucine zipper transcription factor|transcription factor MafB
Swissprots Q9Y5Q3 B3KNE1 Q9H1F1
Accessions EAW76000 Q9Y5Q3 AF086178 AF134157 AAD30106 AK027324 BAG51303 BC028098 AAH28098 BC036689 AAH36689 BQ271704 DA719830 NM_005461 NP_005452
Function Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context. {ECO:0000250, ECO:0000269|PubMed:19143053}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:10444328}.

MafB (B-11) - sc-376387 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MafB (B-11): sc-376387. Western blot analysis of MafB expression in non-transfected: sc-117752 (A) and human MafB transfected: sc-114754 (B) 293T whole cell lysates.

MafB (C-17) - sc-10024 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MafB (E-20) - sc-10023 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MafB (E-20): sc-10023. Western blot analysis of human MafB expression in non-transfected: sc-117750 (A) and human MafB transfected: sc-110001 (B) CHO whole cell lysates.

MafB (F-11) - sc-74521 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MafB (F-11): sc-74521. Western blot analysis of human MafB expression in non-transfected: sc-117750 (A) and human MafB transfected: sc-110001 (B) CHO whole cell lysates.

MafB (H-100) - sc-22830 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MafB (H-100): sc-22830. Western blot analysis of MafB expression in non-transfected: sc-117750 (A) and human MafB transfected: sc-110001 (B) CHO whole cell lysates.

MafB (P-20) - sc-10022 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MafB (P-20): sc-10022. Western blot analysis of MafB expression in HL-60 (A), TF-1 (B) and K-562 (C) whole cell lysates.

c-Maf (M-153) - sc-7866 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
c-Maf (M-153): sc-7866. Western blot analysis of c-Maf expression in control (A) and c-Maf-transfected (B) COS cells.

Anti-MafB antibody - ab66506 from Abcam

Prices $400.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MafB antibody (ab66506) at 1.25 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-MafB antibody - ab65953 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MafB antibody (ab65953) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate Lane 2 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 3 : Caco 2 (Human colonic carcinoma cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-MafB antibody - ab56242 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MafB antibody (ab56242) at 0.25 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP-conjugated anti-rabbit IgG at 1/50000 dilution

Anti-MafB antibody - ab82837 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MafB antibody (ab82837) at 1/500 dilutionLane 1 : uninduced culture of E.coli (one shot Top10 competent cells)Lane 2 : induced culture of E.coli (one shot Top10 competent cells)Secondaryanti-Rabbit IgG HRP at 1/1000 dilution

Anti-MAFB Antibody (aa100-150) - LS-C286588 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse MafB by Immunohistochemistry. Sample: FFPE section of mouse pancreatic islet. Antibody: Affinity purified rabbit anti-MafB used at a dilution of 1:250. Epitope Retrieval Buffer-High pH (IHC-101J) was substituted for Epitope Retrieval Buffer-Reduced pH.

Anti-MAFB Antibody (Internal) - LS-C71988 from LifeSpan Bioscience

Prices $665.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MAFB Antibody (C-Terminus, APC) - LS-C262419 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAFB Antibody (C-Terminus, AP) - LS-C262418 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAFB Antibody (C-Terminus, Biotin) - LS-C262420 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAFB Antibody (C-Terminus, FITC) - LS-C262421 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAFB Antibody (C-Terminus, Azide-free, HRP) - LS-C262422 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAFB Antibody (C-Terminus, PE) - LS-C262423 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAFB Antibody (aa266-292) - LS-C322797 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MAFB Antibody (N-Terminus) - LS-C31805 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
MAFB antibody LS-C31805 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-MAFB Antibody (aa36-85) - LS-C112164 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MAFB antibody LS-C112164 Western blot of Fetal Muscle lysate.

Anti-MAFB Antibody (aa251-300) - LS-C116776 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MAFB antibody LS-C116776 Western blot of OVCAR-3 cell lysate.

Anti-MAFB Antibody (aa41-90) - LS-C30477 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MAFB antibody LS-C30477 was used in IHC to stain formalin-fixed, paraffin-embedded human spleen.

Anti-MAFB Antibody (clone 2F12) - LS-C175251 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F12
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MAFB (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MAFB.
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