MAFB

Gene Symbol	MAFB
Entrez Gene	9935
Alt Symbol	KRML, MCTO
Species	Human
Gene Type	protein-coding
Description	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
Other Description	Kreisler maf-related leucine zipper homolog|MAFB/Kreisler basic region/leucine zipper transcription factor|transcription factor MafB
Swissprots	Q9Y5Q3 B3KNE1 Q9H1F1
Accessions	EAW76000 Q9Y5Q3 AF086178 AF134157 AAD30106 AK027324 BAG51303 BC028098 AAH28098 BC036689 AAH36689 BQ271704 DA719830 NM_005461 NP_005452
Function	Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context. {ECO:0000250, ECO:0000269|PubMed:19143053}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978}.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:10444328}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MafB full length protein - ab132192 from Abcam Category Protein Source Wheat germ Species Human

Human MafB peptide - ab71662 from Abcam Category Peptide

Human MafB protein fragment - ab153027 from Abcam Category Protein Source Wheat germ Species Human

MAFB Antibody Blocking Peptide - LS-E1509 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAFB Antibody Blocking Peptide - LS-E11911 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAFB Antibody Blocking Peptide - LS-E21279 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MAFB Antibody Blocking Peptide - LS-E21280 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MafB Protein - H00009935-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MafB Protein - H00009935-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MAFB-Antibody-C-term-Blocking-peptide - BP12233b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MAFB Protein Lysate (APL10893) - APL10893 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

MAFB - H00009935-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MAFB - H00009935-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MAFB - H00009935-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MAFB - H00009935-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MAFB fusion protein - ag14505 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

MAFB fusion protein - Ag14102 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human Transcription factor MafB(MAFB) - CSB-YP897570HU CSB-EP897570HU CSB-BP897570HU CSB-MP897570HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MafB peptide - ab205727 from Abcam Category Peptide

MafB Recombinant Protein Antigen - NBP1-81342PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MAFB Peptide, Human - M34GP09073H from Creative Peptides Category Peptide Source Synthetic. Species Human

MAFB Protein Lysate - orb333559 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

Recombinant Human MAFB protein, T7/His-tagged - MAFB-218H from Creative Biomart Category Protein Source E. coli Species Human

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