Hmgcl

Gene Symbol	Hmgcl
Entrez Gene	15356
Alt Symbol	AW476067, HL
Species	Mouse
Gene Type	protein-coding
Description	3-hydroxy-3-methylglutaryl-Coenzyme A lyase
Other Description	3-hydroxy-3-methylglutarate-CoA lyase|HMG-CoA lyase|hydroxymethylglutaryl-CoA lyase, mitochondrial
Swissprots	Q8QZS6 P38060
Accessions	AAB03107 EDL29963 P38060 AK077842 AK132035 BAE20956 AK144768 BAE26056 AK145251 BAE26328 AK154033 BAE32329 AK182431 AK210917 AK217644 BB852743 BC025440 AAH25440 BX631310 S65036 AAB27965 XM_006538563 XP_006538626 XM_006538564 XP_006538627 NM_008254 NP_032280
Function	Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta- hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism (By similarity). {ECO:0000250}.
Subcellular Location	Mitochondrion matrix {ECO:0000269|PubMed:7527399}. Peroxisome {ECO:0000269|PubMed:7527399}. Note=Unprocessed form is peroxisomal.
Top Pathways	Peroxisome, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Hepatic lipase, HL, Mouse, ELISA Kit - CSB-E10033m from ARP American Research Products Category ELISA Kit Prices $565.00, $835.00, $837.00, $839.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.156 U/ml Range 0.625 U/ml-40 U/ml

Lipase, Hepatic (LIPC), Mouse, ELISA Kit - SEA769Mu from ARP American Research Products Category ELISA Kit Prices $668.00 Sizes 96 t Sensitivity 0.119ng/mL Range 0.312-20ng/mL

Mouse HL ELISA Kit - MH0260 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase, ELISA Kit - MBS9333073 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse Hepatic lipase ELISA - E03H0253 from BlueGene Biotech Category ELISA Kit Sensitivity 0.1 ng/mL

ELISA Kit for Lipase, Hepatic (LIPC) - SEA769Mu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.126ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Mouse LIPC(Lipase, Hepatic) ELISA Kit - E-EL-M0659 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 0.23 ng/mL Range 0.39~25 ng/mL

Mouse CX26 (Connexin 26) CLIA Kit - E-CL-M0221 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 11.719pg/mL Range 19.531-1250pg/mL

Mouse HL ELISA Kit - E055528 from Biobool Category ELISA Kit Sensitivity 0.06 ng/ml.

Mouse Hmgcl ELISA Kit - E073636 from Biobool Category ELISA Kit

Mouse HL ELISA Kit - EMH0260 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

Mouse Hepatic lipase (HL) ELISA Kit - AE35471MO from ARP American Research Products Category ELISA Kit Prices $612.00 Sizes 96 t Sensitivity 0.126 ng/mL Range 0.312-20 ng/mL

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