Hmgcl

Gene Symbol	Hmgcl
Entrez Gene	15356
Alt Symbol	AW476067, HL
Species	Mouse
Gene Type	protein-coding
Description	3-hydroxy-3-methylglutaryl-Coenzyme A lyase
Other Description	3-hydroxy-3-methylglutarate-CoA lyase|HMG-CoA lyase|hydroxymethylglutaryl-CoA lyase, mitochondrial
Swissprots	Q8QZS6 P38060
Accessions	AAB03107 EDL29963 P38060 AK077842 AK132035 BAE20956 AK144768 BAE26056 AK145251 BAE26328 AK154033 BAE32329 AK182431 AK210917 AK217644 BB852743 BC025440 AAH25440 BX631310 S65036 AAB27965 XM_006538563 XP_006538626 XM_006538564 XP_006538627 NM_008254 NP_032280
Function	Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta- hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism (By similarity). {ECO:0000250}.
Subcellular Location	Mitochondrion matrix {ECO:0000269|PubMed:7527399}. Peroxisome {ECO:0000269|PubMed:7527399}. Note=Unprocessed form is peroxisomal.
Top Pathways	Peroxisome, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Recombinant Lipase, Hepatic (LIPC) - RPA769Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Lipase, Hepatic (LIPC) - RPA769Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Hydroxymethylglutaryl-CoA lyase, mitochondrial(Hmgcl) - CSB-YP010563MO CSB-EP010563MO CSB-BP010563MO CSB-MP010563MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Recombinant Mouse HMGCL Protein - HMGCL-7732M from Creative Biomart Category Protein Source Mammalian Cells Species Mouse

HMGCL Recombinant Protein (OPCD00160) - OPCD00160 from Aviva Systems Biology Category Protein Source E.coli Species Mouse

Hydroxymethylglutaryl-CoA lyase, mitochondrial (Hmgcl), Recombinant Protein - MBS957572 from MyBioSource Category Protein Prices $1,055.00, $1,055.00, $1,285.00, $1,285.00, $1,645.00, $1,645.00, $2,110.00, $2,110.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

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