Hmgcl

Gene Symbol Hmgcl
Entrez Gene 15356
Alt Symbol AW476067, HL
Species Mouse
Gene Type protein-coding
Description 3-hydroxy-3-methylglutaryl-Coenzyme A lyase
Other Description 3-hydroxy-3-methylglutarate-CoA lyase|HMG-CoA lyase|hydroxymethylglutaryl-CoA lyase, mitochondrial
Swissprots Q8QZS6 P38060
Accessions AAB03107 EDL29963 P38060 AK077842 AK132035 BAE20956 AK144768 BAE26056 AK145251 BAE26328 AK154033 BAE32329 AK182431 AK210917 AK217644 BB852743 BC025440 AAH25440 BX631310 S65036 AAB27965 XM_006538563 XP_006538626 XM_006538564 XP_006538627 NM_008254 NP_032280
Function Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta- hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism (By similarity). {ECO:0000250}.
Subcellular Location Mitochondrion matrix {ECO:0000269|PubMed:7527399}. Peroxisome {ECO:0000269|PubMed:7527399}. Note=Unprocessed form is peroxisomal.
Top Pathways Peroxisome, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism

HMGCL CRISPR/Cas9 KO Plasmid (m) - sc-420876 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HMGCL HDR Plasmid (m) - sc-420876-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HMGCL Double Nickase Plasmid (m) - sc-420876-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HMGCL Double Nickase Plasmid (m2) - sc-420876-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HMGCL CRISPR Activation Plasmid (m) - sc-420876-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HMGCL CRISPR Activation Plasmid (m2) - sc-420876-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HMGCL Lentiviral Activation Particles (m) - sc-420876-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HMGCL Lentiviral Activation Particles (m2) - sc-420876-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

HMGCL siRNA (m) - sc-146051 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

HMGCL shRNA Plasmid (m) - sc-146051-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

HMGCL shRNA (m) Lentiviral Particles - sc-146051-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU050141 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN33340 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33340 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

HMGCL siRNA (Mouse) - CRM1848 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

HMGCL - MBS828718 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse HMGCL (NM_008254.2) - SHH313353 from Creative biogene

Category siRNA
Species Reactivities Mouse

HMGCL shRNA Plasmid (Mouse) - CHM1848 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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