Gene Symbol | HMOX1 |
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Entrez Gene | 3162 |
Alt Symbol | HMOX1D, HO-1, HSP32, bK286B10 |
Species | Human |
Gene Type | protein-coding |
Description | heme oxygenase 1 |
Other Description | heat shock protein, 32-kD|heme oxygenase (decycling) 1 |
Swissprots | P09601 |
Accessions | AAR23262 CAA32886 EAW60059 P09601 AF051791 AK313120 BAG35941 BC001491 AAH01491 BP288767 BT019785 AAV38588 CA306357 CR456505 CAG30391 CR541945 CAG46743 CR541968 CAG46766 CU013103 CAK54534 CU013391 CAK54833 DQ892310 ABM83236 DQ895510 ABM86436 GU187011 ACZ72606 GU187012 ACZ72607 JF323038 ADZ76424 M23041 AAA50403 M23042 X06985 CAA30045 NM_002133 NP_002124 |
Function | Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. |
Subcellular Location | Microsome {ECO:0000269|PubMed:22419571}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:22419571}; Peripheral membrane protein {ECO:0000269|PubMed:22419571}; Cytoplasmic side {ECO:0000269|PubMed:22419571}. |
Tissue Specificity | Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level). {ECO:0000269|PubMed:20855888}. |
Top Pathways | Mineral absorption, MicroRNAs in cancer, Porphyrin and chlorophyll metabolism |
HO 1 Human ELISA Kit - ab133064 from Abcam
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HO-1 Human ELISA development set (Reagents forĀ 5 x 96 well plates, without plates) - ab133058 from Abcam
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Human HMOX1 / HO-1 ELISA Kit (Sandwich ELISA) - LS-F4084 from LifeSpan Bioscience
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Mouse HMOX1 / HO-1 ELISA Kit (Sandwich ELISA) - LS-F4086 from LifeSpan Bioscience
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Rat HMOX1 / HO-1 ELISA Kit (Sandwich ELISA) - LS-F4085 from LifeSpan Bioscience
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Rat HMOX1 / HO-1 ELISA Kit (Sandwich ELISA) - LS-F11649 from LifeSpan Bioscience
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Mouse HMOX1 / HO-1 ELISA Kit (Sandwich ELISA) - LS-F11648 from LifeSpan Bioscience
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Human Total HO-1/HMOX1 DuoSet IC Economy Pack, 15 Plate - DYC3776E from R&D Systems
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Human Total HO-1/HMOX1 DuoSet IC ELISA - DYC3776-2 from R&D Systems
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Human Total HO-1/HMOX1 DuoSet IC, 5 Plate - DYC3776-5 from R&D Systems
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Human/Mouse Total HO-1/HMOX1 Cell-Based ELISA - KCB3776 from R&D Systems
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Human Heme Oxygenase 1 ELISA Kit - abx052513 from Abbexa
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Heme Oxygenase 1, Decycling (HO1), Human, ELISA Kit - SEA584Hu from ARP American Research Products
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Heme oxygenase 1, HMOX1, Human, ELISA Kit - E0584h from ARP American Research Products
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Heme oxygenase 1, HO-1, Human, ELISA Kit - CSB-E08266h from ARP American Research Products
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Heme Oxygenase 1, HO1, Human, ELISA Kit - E-EL-H2172 from ARP American Research Products
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Heme Oxygenase 1, HO-1, Mouse, ELISA Kit - E-EL-M0651 from ARP American Research Products
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Heme Oxygenase 1, HO-1, Rat, ELISA Kit - E-EL-R0488 from ARP American Research Products
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Heme Oxygenase 1, HO1, Rabbit, ELISA Kit - E-EL-RB0965 from ARP American Research Products
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Heme Oxygenase 1, HO1, Chicken, ELISA Kit - E-EL-Ch2181 from ARP American Research Products
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Heme Oxygenase 1, HO1, Porcine, ELISA Kit - E-EL-P1413 from ARP American Research Products
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Heme Oxygenase 1, HO1, Sheep, ELISA Kit - E-EL-S0258 from ARP American Research Products
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Heme Oxygenase 1, HO1, Monkey, ELISA Kit - E-EL-MK0047 from ARP American Research Products
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heme oxygenase 1, HO-1, ELISA Kit - MBS9303006 from MyBioSource
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HO-1 ELISA Kit - SKT-111 from StressMarq Bioscience
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