HMOX1

Gene Symbol HMOX1
Entrez Gene 3162
Alt Symbol HMOX1D, HO-1, HSP32, bK286B10
Species Human
Gene Type protein-coding
Description heme oxygenase 1
Other Description heat shock protein, 32-kD|heme oxygenase (decycling) 1
Swissprots P09601
Accessions AAR23262 CAA32886 EAW60059 P09601 AF051791 AK313120 BAG35941 BC001491 AAH01491 BP288767 BT019785 AAV38588 CA306357 CR456505 CAG30391 CR541945 CAG46743 CR541968 CAG46766 CU013103 CAK54534 CU013391 CAK54833 DQ892310 ABM83236 DQ895510 ABM86436 GU187011 ACZ72606 GU187012 ACZ72607 JF323038 ADZ76424 M23041 AAA50403 M23042 X06985 CAA30045 NM_002133 NP_002124
Function Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
Subcellular Location Microsome {ECO:0000269|PubMed:22419571}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:22419571}; Peripheral membrane protein {ECO:0000269|PubMed:22419571}; Cytoplasmic side {ECO:0000269|PubMed:22419571}.
Tissue Specificity Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level). {ECO:0000269|PubMed:20855888}.
Top Pathways Mineral absorption, MicroRNAs in cancer, Porphyrin and chlorophyll metabolism

Heme Oxygenase 1 CRISPR/Cas9 KO Plasmid (h) - sc-400157 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Heme Oxygenase 1 HDR Plasmid (h) - sc-400157-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Heme Oxygenase 1 Double Nickase Plasmid (h) - sc-400157-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Heme Oxygenase 1 Double Nickase Plasmid (h2) - sc-400157-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Heme Oxygenase 1 CRISPR Activation Plasmid (h) - sc-400157-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Heme Oxygenase 1 CRISPR Activation Plasmid (h2) - sc-400157-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Heme Oxygenase 1 Lentiviral Activation Particles (h) - sc-400157-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Heme Oxygenase 1 Lentiviral Activation Particles (h2) - sc-400157-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Heme Oxygenase 1 siRNA (h) - sc-35554 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Heme Oxygenase 1 shRNA Plasmid (h) - sc-35554-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Heme Oxygenase 1 shRNA (h) Lentiviral Particles - sc-35554-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Heme Oxygenase 1 siRNA (h2) - sc-44306 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Heme Oxygenase 1 shRNA Plasmid (h2) - sc-44306-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Heme Oxygenase 1 shRNA (h2) Lentiviral Particles - sc-44306-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU051241 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10180 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10180 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05063 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05063

HMOX1 siRNA (Human) - CRH2158 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HO-1/HMOX1/HSP32 RNAi - H00003162-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

HMOX1 - MBS8212711 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HMOX1 (NM_002133.2) - SHH313525 from Creative biogene

Category siRNA
Species Reactivities Human

Human HMOX1 siRNA - orb262660 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HMOX1 shRNA Plasmid (Human) - CHH2158 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HMOX1 miRNA 3'UTR clone - MiUTR3H-01009 from Creative biogene

Species Reactivities Human
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