Gene Symbol | FAM162A |
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Entrez Gene | 26355 |
Alt Symbol | C3orf28, E2IG5, HGTD-P |
Species | Human |
Gene Type | protein-coding |
Description | family with sequence similarity 162, member A |
Other Description | E2-induced gene 5 protein|HIF-1 alpha-responsive proapoptotic molecule|growth and transformation-dependent protein|protein FAM162A |
Swissprots | Q9UJX8 Q9NRN6 Q96A26 |
Accessions | EAW79486 Q96A26 AF107495 AAG39275 AF191020 AAF09484 AF201944 AAF86880 AF250321 AAG44569 AK026030 AK125835 AK293994 BAG57358 BC010896 AAH10896 BC015060 AAH15060 BI460077 NM_014367 NP_055182 |
Function | Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly. {ECO:0000269|PubMed:15082785}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Mitochondrion {ECO:0000269|PubMed:15082785, ECO:0000269|PubMed:16698020}. |
HGTD-P (H-4) - sc-514243 from Santa Cruz Biotechnology
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HGTD-P (C-15) - sc-99924 from Santa Cruz Biotechnology
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HGTD-P (E-8) - sc-514389 from Santa Cruz Biotechnology
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Anti-FAM162A antibody - ab122295 from Abcam
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Anti-FAM162A / C3orf28 Antibody (aa118-146, AP) - LS-C208924 from LifeSpan Bioscience
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Anti-FAM162A / C3orf28 Antibody (aa118-146, Biotin) - LS-C208929 from LifeSpan Bioscience
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Anti-FAM162A / C3orf28 Antibody (aa118-146, APC) - LS-C208927 from LifeSpan Bioscience
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Anti-FAM162A / C3orf28 Antibody (aa118-146, FITC) - LS-C208930 from LifeSpan Bioscience
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Anti-FAM162A / C3orf28 Antibody (aa118-146, Azide-free, HRP) - LS-C208931 from LifeSpan Bioscience
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Anti-FAM162A / C3orf28 Antibody (aa118-146) - LS-C329525 from LifeSpan Bioscience
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Anti-FAM162A / C3orf28 Antibody (aa118-146, PE) - LS-C208932 from LifeSpan Bioscience
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Anti-FAM162A / C3orf28 Antibody (N-Terminus) - LS-C345662 from LifeSpan Bioscience
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Anti-FAM162A / C3orf28 Antibody (aa118-146) - LS-C167889 from LifeSpan Bioscience
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FAM162A Antibody - NBP1-86792 from Novus Biologicals
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Anti-FAM162A antibody produced in rabbit - HPA035856 from Sigma-Aldrich
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ANTI-F162A (C-TERM) antibody produced in rabbit - SAB1304648 from Sigma-Aldrich
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F162A Antibody - N-terminal region (ARP73955_P050) - ARP73955_P050 from Aviva Systems Biology
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FAM162A Antibody - C-terminal region (OAAB01010) - OAAB01010 from Aviva Systems Biology
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F162A-Antibody-C-term - AP10990b from Abgent, a WuXi AppTec company
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Anti -F162A, CT (FAM162A, C3orf28, E2IG5, Protein FAM162A, E2-induced gene 5 protein,Growth and transformation-dependent protein) - 035306 from USBiological Life Science
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Anti -F162A, CT (FAM162A, C3orf28, E2IG5, Protein FAM162A, E2-induced gene 5 protein,Growth and transformation-dependent protein) (AP) - 035306-AP from USBiological Life Science
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Anti -F162A, CT (FAM162A, C3orf28, E2IG5, Protein FAM162A, E2-induced gene 5 protein,Growth and transformation-dependent protein) (APC) - 035306-APC from USBiological Life Science
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Anti -F162A, CT (FAM162A, C3orf28, E2IG5, Protein FAM162A, E2-induced gene 5 protein,Growth and transformation-dependent protein) (Azide free) (HRP) - 035306-HRP from USBiological Life Science
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Anti -F162A, CT (FAM162A, C3orf28, E2IG5, Protein FAM162A, E2-induced gene 5 protein,Growth and transformation-dependent protein) (Biotin) - 035306-Biotin from USBiological Life Science
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Anti -F162A, CT (FAM162A, C3orf28, E2IG5, Protein FAM162A, E2-induced gene 5 protein,Growth and transformation-dependent protein) (FITC) - 035306-FITC from USBiological Life Science
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