Gene Symbol | FAM162A |
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Entrez Gene | 26355 |
Alt Symbol | C3orf28, E2IG5, HGTD-P |
Species | Human |
Gene Type | protein-coding |
Description | family with sequence similarity 162, member A |
Other Description | E2-induced gene 5 protein|HIF-1 alpha-responsive proapoptotic molecule|growth and transformation-dependent protein|protein FAM162A |
Swissprots | Q9UJX8 Q9NRN6 Q96A26 |
Accessions | EAW79486 Q96A26 AF107495 AAG39275 AF191020 AAF09484 AF201944 AAF86880 AF250321 AAG44569 AK026030 AK125835 AK293994 BAG57358 BC010896 AAH10896 BC015060 AAH15060 BI460077 NM_014367 NP_055182 |
Function | Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly. {ECO:0000269|PubMed:15082785}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Mitochondrion {ECO:0000269|PubMed:15082785, ECO:0000269|PubMed:16698020}. |
Human FAM162A full length protein - ab161977 from Abcam
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FAM162A / C3orf28 Antibody Blocking Peptide - LS-E649 from LifeSpan Bioscience
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Recombinant Human FAM162A Protein - H00026355-P01 from Novus Biologicals
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F162A-Antibody-C-term-Blocking-peptide - BP10990b from Abgent, a WuXi AppTec company
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FAM162A - H00026355-P01-10 from Acris Antibodies
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FAM162A - H00026355-P01-25 from Acris Antibodies
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FAM162A - TP303056 from Acris Antibodies
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FAM162A Recombinant Protein Antigen - NBP1-86792PEP from Novus Biologicals
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FAM162A Peptide, Human - M34GP05297H from Creative Peptides
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FAM162A Recombinant Protein Antigen - NBP2-58663PEP from Novus Biologicals
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Protein FAM162A (FAM162A), Recombinant Protein - MBS7014538 from MyBioSource
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Protein FAM162A (FAM162A), Recombinant Protein - MBS7014540 from MyBioSource
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