HJURP

Gene Symbol	HJURP
Entrez Gene	55355
Alt Symbol	FAKTS, URLC9, hFLEG1
Species	Human
Gene Type	protein-coding
Description	Holliday junction recognition protein
Other Description	14-3-3-associated AKT substrate|fetal liver expressing gene 1|fetal liver-expressing gene 1 protein|up-regulated in lung cancer 9
Swissprots	A8IRH5 Q9NSL8 Q9BUT2 B4DWR0 Q8NCD3 B4DZV4
Accessions	EAW71064 EAW71065 Q8NCD3 AB101211 BAF82039 AB162218 BAD36741 AK074809 BAC11221 AK301643 BAG63122 AK303109 BAG64216 AL162048 CAB82391 BC001940 AAH01940 BE535238 BM148072 BM475244 BM838206 BQ225710 CA441903 CF619091 DB022872 DB319863 DN998761 XM_011511437 XP_011509739 NM_001282962 NP_001269891 NM_001282963 NP_001269892 NM_018410 NP_060880
Function	Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions. {ECO:0000269|PubMed:19410544, ECO:0000269|PubMed:19410545}.
Subcellular Location	Nucleus, nucleolus. Chromosome, centromere. Note=Localizes in centromeres during late telophase and early G1, when CENPA nucleosomes are assembled. Localizes to nucleolus during S phase, nucleolus site being often related to storage.
Tissue Specificity	According to PubMed:17256767, highly expressed in the thymus with lower levels in the placenta, small intestine, liver, skeletal muscle, and colon. According to PubMed:17823411, highly expressed in testis, and at a relatively lower level in thymus and bone marrow. Significantly overexpressed in many lung cancer samples, compared with normal lung. {ECO:0000269|PubMed:17256767, ECO:0000269|PubMed:17823411}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HJURP Antibody Blocking Peptide - LS-E2413 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HJURP-Antibody-C-term-Blocking-peptide - BP13406b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human HJURP protein - orb244271 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

HJURP fusion protein - ag7402 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Holliday junction recognition protein(HJURP) - CSB-YP010467HU CSB-BP010467HU CSB-MP010467HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Holliday junction recognition protein - CSB-EP010467HU from Cusabio Category Protein Source E.coli Species Human

HJURP Recombinant Protein Antigen - NBP1-85025PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HJURP Peptide, Human - M34GP07080H from Creative Peptides Category Peptide Source Synthetic. Species Human

HJURP Recombinant Protein (OPCA01644) - OPCA01644 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant human Holliday junction recognition protein - AP70393 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

HJURP Recombinant Protein Antigen - NBP2-58281PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

Holliday junction recognition, Recombinant Protein - MBS9420316 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Human

Holliday junction recognition, Recombinant Protein - MBS1354971 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $1,180.00, $1,560.00, $1,790.00, $1,790.00, $2,690.00, $3,130.00, $3,130.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Recombinant Human HJURP Protein, His-SUMO-tagged - HJURP-4230H from Creative Biomart Category Protein Source E. coli Species Human

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