HJURP

Gene Symbol	HJURP
Entrez Gene	55355
Alt Symbol	FAKTS, URLC9, hFLEG1
Species	Human
Gene Type	protein-coding
Description	Holliday junction recognition protein
Other Description	14-3-3-associated AKT substrate\|fetal liver expressing gene 1\|fetal liver-expressing gene 1 protein\|up-regulated in lung cancer 9
Swissprots	A8IRH5 Q9NSL8 Q9BUT2 B4DWR0 Q8NCD3 B4DZV4
Accessions	EAW71064 EAW71065 Q8NCD3 AB101211 BAF82039 AB162218 BAD36741 AK074809 BAC11221 AK301643 BAG63122 AK303109 BAG64216 AL162048 CAB82391 BC001940 AAH01940 BE535238 BM148072 BM475244 BM838206 BQ225710 CA441903 CF619091 DB022872 DB319863 DN998761 XM_011511437 XP_011509739 NM_001282962 NP_001269891 NM_001282963 NP_001269892 NM_018410 NP_060880
Function	Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions. {ECO:0000269\|PubMed:19410544, ECO:0000269\|PubMed:19410545}.
Subcellular Location	Nucleus, nucleolus. Chromosome, centromere. Note=Localizes in centromeres during late telophase and early G1, when CENPA nucleosomes are assembled. Localizes to nucleolus during S phase, nucleolus site being often related to storage.
Tissue Specificity	According to PubMed:17256767, highly expressed in the thymus with lower levels in the placenta, small intestine, liver, skeletal muscle, and colon. According to PubMed:17823411, highly expressed in testis, and at a relatively lower level in thymus and bone marrow. Significantly overexpressed in many lung cancer samples, compared with normal lung. {ECO:0000269\|PubMed:17256767, ECO:0000269\|PubMed:17823411}.

HJURP (A-14) - sc-168089 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

HJURP (A-14): sc-168089. Western blot analysis of HJURP expression in Hs 67 whole cell lysate.

HJURP (H-277) - sc-134696 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

HJURP (S-14) - sc-168091 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-HJURP antibody - ab100800 from Abcam

Prices	$384.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human skin carcinoma tissue labelling HJURP with ab100800 at 1/1000 (1µg/mg). Detection: DAB.

Anti-HJURP antibody [HOPE169E] - ab175577 from Abcam

Prices	$384.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	HOPE169E

Immunohistochemical analysis of frozen cytospin preparations of HEK293T cells expressing HJURP (left and right panel) or A-MYB (central panel) as negative control. The left and central panels were incubated with ab175577, labeling HJURP. The right panel was incubated with an antibody against the expression vector itself (positive control).

Anti-HJURP Antibody (aa558-588, AP) - LS-C258577 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HJURP Antibody (aa558-588, FITC) - LS-C258580 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HJURP Antibody (aa558-588, APC) - LS-C258578 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HJURP Antibody (aa558-588, PE) - LS-C258582 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HJURP Antibody (aa558-588, Biotin) - LS-C258579 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HJURP Antibody (aa558-588, Azide-free, HRP) - LS-C258581 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HJURP Antibody (aa700-748) - LS-C289535 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HJURP Antibody (aa558-588) - LS-C329634 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-HJURP Antibody (aa650-700) - LS-C289534 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human HJURP by Immunohistochemistry. Sample: FFPE section of human skin carcinoma. Antibody: Affinity purified rabbit anti-HJURP used at a dilution of 1:1000 (1 ug/mg).

Anti-HJURP Antibody (aa559-588) - LS-C164907 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

HJURP Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human thyroid tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

HJURP Antibody - NBP1-85025 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: HJURP Antibody [NBP1-85025] - Analysis in human cell line WM-115.

HJURP Antibody - 26650002 from Novus Biologicals

Prices	$329.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

HJURP Antibody - NBP1-47287 from Novus Biologicals

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry: HJURP Antibody [NBP1-47287] - Sample: FFPE section of human skin carcinoma. Antibody: Affinity purified rabbit anti-HJURP used at a dilution of 1:1,000 (1ug/ml) Detection: DAB staining using Immunohistochemistry Accessory Kit

HJURP Antibody - NBP1-47288 from Novus Biologicals

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

ANTI-HJURP (C-TERM) antibody produced in rabbit - SAB1303489 from Sigma-Aldrich

Prices	$326.50
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>HJURP (C-term): <B>Cat. No. SAB1303489</B>: HJURP in Human thyroid tissue with HJURP antibody (C-term) at 12.5 μg/mL.

Anti-HJURP antibody produced in rabbit - HPA008436 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-HJURP: <B>Cat. No. HPA008436</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human prostate shows strong cytoplasmic positivity in glandular cells.

HJURP-Antibody-C-term - AP13406b from Abgent, a WuXi AppTec company

Prices	$99.00, $295.00
Sizes	80 µl, 400 µl
Host	Rabbit
Clonality	Polyclonal

HJURP Antibody (C-term) (Cat. #AP13406b) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the HJURP antibody detected the HJURP protein (arrow).

HJURP Antibody - C-terminal region (OAAB09715) - OAAB09715 from Aviva Systems Biology

Prices	$289.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti -HJURP, CT (HJURP, FAKTS, FLEG1, URLC9, Holliday junction recognition protein,14-3-3-associated AKT substrate, Fetal liver-expressing gene 1 protein, Up-regulated inlung cancer 9) - 036613 from USBiological Life Science

Host	Rabbit
Clonality	Polyclonal

Anti -HJURP, CT (HJURP, FAKTS, FLEG1, URLC9, Holliday junction recognition protein,14-3-3-associated AKT substrate, Fetal liver-expressing gene 1 protein, Up-regulated inlung cancer 9) (AP) - 036613-AP from USBiological Life Science

Host	Rabbit
Clonality	Polyclonal

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