HJURP

Gene Symbol HJURP
Entrez Gene 55355
Alt Symbol FAKTS, URLC9, hFLEG1
Species Human
Gene Type protein-coding
Description Holliday junction recognition protein
Other Description 14-3-3-associated AKT substrate|fetal liver expressing gene 1|fetal liver-expressing gene 1 protein|up-regulated in lung cancer 9
Swissprots A8IRH5 Q9NSL8 Q9BUT2 B4DWR0 Q8NCD3 B4DZV4
Accessions EAW71064 EAW71065 Q8NCD3 AB101211 BAF82039 AB162218 BAD36741 AK074809 BAC11221 AK301643 BAG63122 AK303109 BAG64216 AL162048 CAB82391 BC001940 AAH01940 BE535238 BM148072 BM475244 BM838206 BQ225710 CA441903 CF619091 DB022872 DB319863 DN998761 XM_011511437 XP_011509739 NM_001282962 NP_001269891 NM_001282963 NP_001269892 NM_018410 NP_060880
Function Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions. {ECO:0000269|PubMed:19410544, ECO:0000269|PubMed:19410545}.
Subcellular Location Nucleus, nucleolus. Chromosome, centromere. Note=Localizes in centromeres during late telophase and early G1, when CENPA nucleosomes are assembled. Localizes to nucleolus during S phase, nucleolus site being often related to storage.
Tissue Specificity According to PubMed:17256767, highly expressed in the thymus with lower levels in the placenta, small intestine, liver, skeletal muscle, and colon. According to PubMed:17823411, highly expressed in testis, and at a relatively lower level in thymus and bone marrow. Significantly overexpressed in many lung cancer samples, compared with normal lung. {ECO:0000269|PubMed:17256767, ECO:0000269|PubMed:17823411}.

HJURP CRISPR/Cas9 KO Plasmid (h) - sc-405278 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HJURP HDR Plasmid (h) - sc-405278-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HJURP Double Nickase Plasmid (h) - sc-405278-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HJURP Double Nickase Plasmid (h2) - sc-405278-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HJURP CRISPR Activation Plasmid (h) - sc-405278-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HJURP CRISPR Activation Plasmid (h2) - sc-405278-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HJURP Lentiviral Activation Particles (h) - sc-405278-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HJURP Lentiviral Activation Particles (h2) - sc-405278-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HJURP siRNA (h) - sc-94530 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HJURP shRNA Plasmid (h) - sc-94530-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HJURP shRNA (h) Lentiviral Particles - sc-94530-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU027371 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10124 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10124 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

HJURP siRNA (Human) - CRJ0683 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HJURP - MBS8235216 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HJURP shRNA Plasmid (Human) - CHJ0683 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HJURP miRNA 3'UTR clone - MiUTR1H-02856 from Creative biogene

Species Reactivities Human
Search more