Gene Symbol | LPIN2 |
---|---|
Entrez Gene | 9663 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | lipin 2 |
Other Description | lipin-2|phosphatidate phosphatase LPIN2 |
Swissprots | D3DUH3 A7MD25 Q92539 |
Accessions | EAX01686 EAX01687 Q92539 BC152448 AAI52449 BC160018 AAI60018 BQ014306 D87436 BAA13380 XM_005258177 XP_005258234 XM_005258178 XP_005258235 XM_005258179 XP_005258236 XR_935074 NM_014646 NP_055461 |
Function | Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}. Note=Translocates to endoplasmic reticulum membrane with increasing levels of oleate. {ECO:0000250}. |
Tissue Specificity | Expressed in liver, lung, kidney, placenta, spleen, thymus, lymph node, prostate, testes, small intestine, and colon. {ECO:0000269|PubMed:15994876, ECO:0000269|PubMed:17158099}. |
Top Pathways | Glycerolipid metabolism, Glycerophospholipid metabolism |
Lipin-2 (G-7) - sc-514353 from Santa Cruz Biotechnology
|
||||||||||
Lipin-2 (D-18) - sc-68201 from Santa Cruz Biotechnology
|
||||||||||
Lipin-2 (E-17) - sc-50053 from Santa Cruz Biotechnology
|
||||||||||
Lipin-2 (H-160) - sc-134433 from Santa Cruz Biotechnology
|
||||||||||
Lipin-2 (K-20) - sc-50054 from Santa Cruz Biotechnology
|
||||||||||
Anti-Lipin 2 antibody - ab63928 from Abcam
|
||||||||||
Anti-Lipin 2 antibody - ab28765 from Abcam
|
||||||||||
Anti-Lipin 2 antibody [EPR12479] - ab176347 from Abcam
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (N-Terminus) - LS-C37205 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (aa881-896) - LS-C55065 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody - LS-C125876 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (clone 2518C6a) - LS-C184722 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (Internal, AP) - LS-C278923 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (Internal, Biotin) - LS-C278926 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (Internal, APC) - LS-C278925 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (Internal, Azide-free, HRP) - LS-C278928 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (Internal, FITC) - LS-C278927 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (aa275-325) - LS-C290358 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (C-Terminus) - LS-C145511 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (Internal, PE) - LS-C278929 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (Internal) - LS-C327765 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody - LS-C146975 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (aa375-425) - LS-C290359 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (clone 2518C6a) - LS-C342751 from LifeSpan Bioscience
|
||||||||||
Anti-LPIN2 / Lipin 2 Antibody (aa262-288) - LS-C165851 from LifeSpan Bioscience
|