LPIN2

Gene Symbol LPIN2
Entrez Gene 9663
Alt Symbol -
Species Human
Gene Type protein-coding
Description lipin 2
Other Description lipin-2|phosphatidate phosphatase LPIN2
Swissprots D3DUH3 A7MD25 Q92539
Accessions EAX01686 EAX01687 Q92539 BC152448 AAI52449 BC160018 AAI60018 BQ014306 D87436 BAA13380 XM_005258177 XP_005258234 XM_005258178 XP_005258235 XM_005258179 XP_005258236 XR_935074 NM_014646 NP_055461
Function Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Cytoplasm, cytosol {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}. Note=Translocates to endoplasmic reticulum membrane with increasing levels of oleate. {ECO:0000250}.
Tissue Specificity Expressed in liver, lung, kidney, placenta, spleen, thymus, lymph node, prostate, testes, small intestine, and colon. {ECO:0000269|PubMed:15994876, ECO:0000269|PubMed:17158099}.
Top Pathways Glycerolipid metabolism, Glycerophospholipid metabolism

Lipin-2 CRISPR/Cas9 KO Plasmid (h) - sc-411307 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lipin-2 HDR Plasmid (h) - sc-411307-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lipin-2 Double Nickase Plasmid (h) - sc-411307-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lipin-2 Double Nickase Plasmid (h2) - sc-411307-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lipin-2 CRISPR Activation Plasmid (h) - sc-411307-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lipin-2 CRISPR Activation Plasmid (h2) - sc-411307-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lipin-2 Lentiviral Activation Particles (h) - sc-411307-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lipin-2 Lentiviral Activation Particles (h2) - sc-411307-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Lipin-2 siRNA (h) - sc-60942 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Lipin-2 shRNA Plasmid (h) - sc-60942-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Lipin-2 shRNA (h) Lentiviral Particles - sc-60942-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU010371 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12656 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12656 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

LPIN2 siRNA (Human) - CRH6438 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Lpin2 (NM_014646.2) - SHH333583 from Creative biogene

Category siRNA
Species Reactivities Human

LPIN2 shRNA Plasmid (Human) - CHH6438 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LPIN2 miRNA 3'UTR clone - MiUTR1H-05883 from Creative biogene

Species Reactivities Human
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