Gene Symbol | ACOT2 |
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Entrez Gene | 10965 |
Alt Symbol | CTE-IA, CTE1A, MTE1, PTE2, PTE2A, ZAP128 |
Species | Human |
Gene Type | protein-coding |
Description | acyl-CoA thioesterase 2 |
Other Description | acyl-coenzyme A thioester hydrolase 2a|acyl-coenzyme A thioesterase 2, mitochondrial|long-chain acyl-CoA thioesterase 2|mitochondrial acyl-CoA thioesterase 1|peroxisomal long-chain acyl-coA thioesterase 2 |
Swissprots | Q3I5F8 P49753 Q9NUX4 Q53EK4 |
Accessions | P49753 AI537078 AK001939 BAA91989 AK093131 BAG52662 AK223635 BAD97355 AY005822 AAF97985 BC004436 AAH04436 BC006335 AAH06335 BC006500 AAH06500 DQ082755 AAZ31237 DQ893488 ABM84414 DQ896406 ABM87405 L40401 AAC42007 XM_006720007 XP_006720070 NM_006821 NP_006812 NR_046028 |
Function | Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs. {ECO:0000269|PubMed:10944470}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:16940157}. |
Tissue Specificity | Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas. {ECO:0000269|PubMed:16940157}. |
Top Pathways | Ovarian steroidogenesis, Fatty acid elongation, Biosynthesis of unsaturated fatty acids |
ACOT2 Antibody Blocking Peptide - LS-E15570 from LifeSpan Bioscience
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ACOT2 Blocking Peptide - 33R-8680 from Fitzgerald
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ACOT2 fusion protein - ag8093 from Proteintech Group
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ACOT2 fusion protein - Ag8162 from Proteintech Group
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Recombinant Human ACOT2, His-tagged - ACOT2-3139H from Creative Biomart
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ACOT2 Blocking Peptide - CBP3385 from Cohesion Biosciences
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ACOT2 (T209) Peptide - BS3060P from Bioworld Technology
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Recombinant Human Acyl-coenzyme A thioesterase 2, mitochondrial(ACOT2) ,partial - CSB-YP001166HU CSB-EP001166HU CSB-BP001166HU CSB-MP001166HU from Cusabio
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Acyl-coenzyme A thioesterase 2, mitochondrial(ACOT2) ,partial - MBS956639 from MyBioSource
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Recombinant Human ACOT2 protein, GST-tagged - ACOT2-12H from Creative Biomart
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ACOT2 Blocking Peptide - abx162247 from Abbexa
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ZAP128-Antibody-Center-Blocking-peptide - BP5301c from Abgent, a WuXi AppTec company
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ACOT2-Antibody-Center-Blocking-peptide - BP5652c from Abgent, a WuXi AppTec company
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ACOT2 Peptide, Human - M34GP00144H from Creative Peptides
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