Gene Symbol | ACOT2 |
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Entrez Gene | 10965 |
Alt Symbol | CTE-IA, CTE1A, MTE1, PTE2, PTE2A, ZAP128 |
Species | Human |
Gene Type | protein-coding |
Description | acyl-CoA thioesterase 2 |
Other Description | acyl-coenzyme A thioester hydrolase 2a|acyl-coenzyme A thioesterase 2, mitochondrial|long-chain acyl-CoA thioesterase 2|mitochondrial acyl-CoA thioesterase 1|peroxisomal long-chain acyl-coA thioesterase 2 |
Swissprots | Q3I5F8 P49753 Q9NUX4 Q53EK4 |
Accessions | P49753 AI537078 AK001939 BAA91989 AK093131 BAG52662 AK223635 BAD97355 AY005822 AAF97985 BC004436 AAH04436 BC006335 AAH06335 BC006500 AAH06500 DQ082755 AAZ31237 DQ893488 ABM84414 DQ896406 ABM87405 L40401 AAC42007 XM_006720007 XP_006720070 NM_006821 NP_006812 NR_046028 |
Function | Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs. {ECO:0000269|PubMed:10944470}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:16940157}. |
Tissue Specificity | Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas. {ECO:0000269|PubMed:16940157}. |
Top Pathways | Ovarian steroidogenesis, Fatty acid elongation, Biosynthesis of unsaturated fatty acids |
ACOT1/2 (E-1) - sc-373919 from Santa Cruz Biotechnology
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ACOT1/2 (F-2) - sc-373917 from Santa Cruz Biotechnology
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ACOT1/2 (F-6) - sc-398505 from Santa Cruz Biotechnology
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ACOT1/2 (G-20) - sc-82473 from Santa Cruz Biotechnology
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ACOT1/2 (H-76) - sc-135341 from Santa Cruz Biotechnology
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ACOT2 (A-12) - sc-82476 from Santa Cruz Biotechnology
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ACOT2 (G-17) - sc-82477 from Santa Cruz Biotechnology
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ACOT2 (H-45) - sc-135340 from Santa Cruz Biotechnology
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ACOT2 (N-18) - sc-82478 from Santa Cruz Biotechnology
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Anti-acyl-CoA Thioesterase 2 antibody - ab84644 from Abcam
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Anti-acyl-CoA Thioesterase 2 antibody - ab135905 from Abcam
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Anti-ACOT2 Antibody (Thr209) - LS-C192073 from LifeSpan Bioscience
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Anti-ACOT2 Antibody (aa171-220) - LS-C119693 from LifeSpan Bioscience
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Anti-ACOT2 Antibody (aa360-409) - LS-C101957 from LifeSpan Bioscience
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Anti-ACOT2 Antibody (aa160-209) - LS-C200079 from LifeSpan Bioscience
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ACOT2 Antibody - NBP1-70402 from Novus Biologicals
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ACOT2 Antibody - NBP1-70841 from Novus Biologicals
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ACOT2 Antibody - H00010965-B01P-50ug from Novus Biologicals
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Anti-ACOT2 antibody produced in rabbit - SAB2100030 from Sigma-Aldrich
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Anti-ACOT2 antibody produced in mouse - SAB1412796 from Sigma-Aldrich
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Anti-ACOT2 antibody produced in rabbit - SAB4500184 from Sigma-Aldrich
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ACOT2 antibody - middle region (ARP42322_P050) - ARP42322_P050 from Aviva Systems Biology
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ACOT2 antibody - GTX87970 from GeneTex
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Anti -ACOT2 (ACOT2, Acyl CoA Thioesterase 2, Acyl coenzyme A thioester Hydrolase 2a, Acylcoenzyme A Thioesterase 2, Mitochondrial, CTE Ia, CTE1A, Long Chain acyl CoA Thioesterase2, Mitochondrial acyl CoA Thioesterase 1, Mitochondrial acyl CoA Thioesterase 2, - 220552 from USBiological Life Science
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ACOT2 Antibody (OAAF03228) - OAAF03228 from Aviva Systems Biology
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