FBXO22

Gene Symbol	FBXO22
Entrez Gene	26263
Alt Symbol	FBX22, FISTC1
Species	Human
Gene Type	protein-coding
Description	F-box protein 22
Other Description	F-box only protein 22|F-box protein FBX22p44|FIST domain containing 1
Swissprots	Q8IXW3 Q9H824 Q8NEZ5 Q6PIL5 Q9UKC0 Q0D2P8
Accessions	AAF04523 EAW99229 EAW99230 EAW99231 EAW99232 Q8NEZ5 AK024048 BAB14798 AK026282 AK223500 BAD97220 AK294311 BAG57588 AK307084 AL705285 AL705308 AW292124 AY005144 AAF89095 BC020204 AAH20204 BC032540 AAH32540 BC039024 AAH39024 BC041691 AAH41691 BE738571 BG328756 HQ448526 ADQ33005 XM_011521447 XP_011519749 NM_012170 NP_036302 NM_147188 NP_671717 NR_037623
Function	Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function. {ECO:0000269|PubMed:22972877}.
Subcellular Location	Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}.
Tissue Specificity	Predominantly expressed in liver, also enriched in cardiac muscle. {ECO:0000269|PubMed:22972877}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FBXO22 full length protein - ab161951 from Abcam Category Protein Source Wheat germ Species Human

FBXO22 Antibody Blocking Peptide - LS-E6113 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FBXO22 Antibody Blocking Peptide - LS-E19782 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FBXO22 Antibody Blocking Peptide - LS-E19783 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human FBXO22 Protein - H00026263-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FBXO22-Antibody-C-term-Blocking-Peptide - BP18732b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FBXO22 Blocking Peptide - 33R-1651 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FBXO22 - H00026263-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

FBXO22 - H00026263-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FBXO22 fusion protein - Ag4485 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

FBXO22 fusion protein - Ag5294 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human FBXO22, GST-tagged - FBXO22-12790H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human F-box only protein 22(FBXO22) - CSB-YP854115HU CSB-EP854115HU CSB-BP854115HU CSB-MP854115HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FBXO22 Protein - abx163210 from Abbexa Category Protein Species Human

FBXO22 (full length, N-term HIS tag, transcript variant 1) - TP760168 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

FBXO22 Peptide, Human - M34GP05592H from Creative Peptides Category Peptide Source Synthetic. Species Human

F-box only protein 22 (FBXO22), Recombinant Protein - MBS1466843 from MyBioSource Category Protein Prices $1,175.00, $1,175.00, $1,395.00, $1,395.00, $1,885.00, $1,885.00, $2,350.00, $2,350.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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