FBXO22

Gene Symbol	FBXO22
Entrez Gene	26263
Alt Symbol	FBX22, FISTC1
Species	Human
Gene Type	protein-coding
Description	F-box protein 22
Other Description	F-box only protein 22|F-box protein FBX22p44|FIST domain containing 1
Swissprots	Q8IXW3 Q9H824 Q8NEZ5 Q6PIL5 Q9UKC0 Q0D2P8
Accessions	AAF04523 EAW99229 EAW99230 EAW99231 EAW99232 Q8NEZ5 AK024048 BAB14798 AK026282 AK223500 BAD97220 AK294311 BAG57588 AK307084 AL705285 AL705308 AW292124 AY005144 AAF89095 BC020204 AAH20204 BC032540 AAH32540 BC039024 AAH39024 BC041691 AAH41691 BE738571 BG328756 HQ448526 ADQ33005 XM_011521447 XP_011519749 NM_012170 NP_036302 NM_147188 NP_671717 NR_037623
Function	Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function. {ECO:0000269|PubMed:22972877}.
Subcellular Location	Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}.
Tissue Specificity	Predominantly expressed in liver, also enriched in cardiac muscle. {ECO:0000269|PubMed:22972877}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FBXO22 (S-14) - sc-164371 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

FBXO22 (FF-7) - sc-100736 from Santa Cruz Biotechnology Prices $295.00 Sizes 100 µg/ml Host Mouse Clonality Monoclonal

Anti-FBXO22 antibody - ab57055 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-FBXO22 antibody - C-terminal - ab138564 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-FBXO22 Antibody (aa1-300, clone 10C200, Azide-free) - LS-C183618 from LifeSpan Bioscience Host Mouse Clonality Monoclonal Clone 10C200

Anti-FBXO22 Antibody (aa190-239) - LS-C145712 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-FBXO22 Antibody (C-Terminus) - LS-C102570 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-FBXO22 Antibody (aa320-347, FITC) - LS-C235216 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO22 Antibody (aa320-347, PE) - LS-C235217 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO22 Antibody (aa320-347) - LS-C159632 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-FBXO22 Antibody (aa320-347, AP) - LS-C246931 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO22 Antibody (aa320-347, Biotin) - LS-C246932 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO22 Antibody (aa320-347, APC) - LS-C246934 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO22 Antibody - LS-C307501 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-FBXO22 Antibody (aa320-347, Azide-free, HRP) - LS-C249972 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-FBXO22 Antibody (Internal) - LS-C345793 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-FBXO22 Antibody (aa319-347) - LS-C321318 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

FBXO22 Antibody - NBP1-55425 from Novus Biologicals Prices $369.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

FBXO22 Antibody (6G9) - H00026263-M01 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6G9

FBXO22 Antibody - NBP2-16447 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-FBXO22 antibody produced in rabbit - SAB2701330 from Sigma-Aldrich Prices $326.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-FBXO22 antibody produced in rabbit - SAB2100781 from Sigma-Aldrich Prices $347.50 Sizes 100 µl Host Rabbit Clonality Polyclonal

Monoclonal Anti-FBXO22 antibody produced in mouse - WH0026263M1 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 6G9

FBXO22 antibody - middle region (ARP54860_P050) - ARP54860_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

FBX22 Antibody - middle region (ARP74522_P050) - ARP74522_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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