NEK1

Gene Symbol NEK1
Entrez Gene 4750
Alt Symbol NY-REN-55, SRPS2, SRPS2A, SRTD6
Species Human
Gene Type protein-coding
Description NIMA-related kinase 1
Other Description NIMA (never in mitosis gene a)-related kinase 1|never in mitosis A-related kinase 1|nimA-related protein kinase 1|protein-serine/threonine kinase|renal carcinoma antigen NY-REN-55|serine/threonine-protein kinase Nek1
Swissprots Q5H9T1 Q9Y594 Q05DG5 G5E9Z3 Q96PY6 Q96SS2 Q9H6P7 Q6PIB8 Q14CB7
Accessions EAX04787 EAX04788 EAX04789 EAX04790 EAX04791 Q96PY6 AB067488 BAB67794 AF155113 AAD42879 AI984346 AK025658 BAB15207 AK027580 BAB55209 AL050385 CAI46225 BC015147 AAH15147 BC037790 AAH37790 BC068201 BC114491 AAI14492 CD358162 CR933642 CAI45943 CR936672 DA697159 Z25431 CAA80918 XM_006714228 XP_006714291 XM_011532003 XP_011530305 XM_011532004 XP_011530306 XM_011532005 XP_011530307 NM_001199397 NP_001186326 NM_001199398 NP_001186327 NM_001199399 NP_001186328 NM_001199400 NP_001186329 NM_012224 NP_036356
Function Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Implicated in the control of meiosis (By similarity). Involved in cilium assembly. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death. {ECO:0000250, ECO:0000269|PubMed:20230784, ECO:0000269|PubMed:21211617}.
Subcellular Location Nucleus {ECO:0000305|PubMed:21211617}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Associated with the pericentriolar material. Localizes to centrosome during interphase and mitosis (By similarity). {ECO:0000250}.
Tissue Specificity High fetal expression in the brain and kidney. {ECO:0000269|PubMed:21211617}.

Nek1 (E-10) - sc-398813 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Nek1 (E-10): sc-398813. Western blot analysis of Nek1 expression in non-transfected 293: sc-110760 (A), mouse Nek1 transfected 293: sc-178990 (B) and PANC-1 (C) whole cell lysates.

Nek1 (M-19) - sc-7437 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Nek1 (M-19): sc-7437. Western blot analysis of Nek1 expression in non-transfected: sc-110760 (A) and mouse Nek1 transfected: sc-178990 (B) 293 whole cell lysates.

Anti-NEK1 antibody - ab198699 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human lymphoma tissue labeling NEK1 using ab198699 at a 1/25 dilution.

Anti-NEK1 antibody - ab186519 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human breast tissue, labeling NEK1 using ab186519 at a 1/200 dilution.

Anti-NEK1 Antibody (aa1165-1196) - LS-C101164 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

NEK1 Antibody - NBP1-82883 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: NEK1 Antibody [NBP1-82883] - Staining of human cell line U-251 MG shows positivity in nuclear membrane.

NEK1 Antibody - NBP2-36534 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NEK1 Antibody [NBP2-36534] - Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit antiNEK1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

NEK1 Antibody - NBP1-82884 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: NEK1 Antibody [NBP1-82884] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells.

NEK1 Antibody - NBP2-36533 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NEK1 Polyclonal Antibody - bs-7814R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NEK1 antibody produced in rabbit - HPA040413 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NEK1: <B>Cat. No. HPA040413</B>: Immunohistochemical staining of human breast shows strong cytoplasmic and membranous positivity in glandular cells.

Anti-NEK1 (C-term) antibody produced in rabbit - SAB1300453 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NEK1 (C-term) Antibody: <B>Cat. No. SAB1300453</B>: NEK1 in human hepatocarcinoma tissue with Anti-NEK1 (C-term) Antibody at 40 μg/mL.

Anti-NEK1 antibody produced in rabbit - HPA020873 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NEK1: <B>Cat. No. HPA020873</B>: Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.

NEK1-Antibody-C-term - AP8072b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Nek1 antibody - GTX111463 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-Nek1 antibody used in ICC/IF. GTX111463

NEK1 Antibody - C-terminal region (OAAB17433) - OAAB17433 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

NEK1 antibody - orb100828 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

NEK1 antibody (FITC) - orb103079 from Biorbyt

Prices $315.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

NEK1 (C-term) antibody - AP15020PU-N from Acris Antibodies

Prices $330.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

NEK1 antibody - PAB3282 from Acris Antibodies

Prices $420.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with NEK1 polyclonal antibody ( Cat # PAB3282 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma.

NEK1 Antibody - 37377 from Signalway Antibody

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human lymphoma tissue using #37377 at dilution 1/25.

NEK1 Polyclonal Antibody - ESAP16567 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of Human lung cancer using NEK1 Polyclonal Antibody at dilution of 1:25

NEK1 Antibody - A304-569A from Bethyl Labs

Prices $99.00, $339.00
Sizes 10 µl (1 mg/ml), 100 µl (1 mg/ml)
Host Rabbit
Clonality Polyclonal

NEK1 Antibody - A304-570A from Bethyl Labs

Prices $99.00, $229.00, $339.00
Sizes 20 µl (2 blots), 100 µl (10 blots), 100 µl (1 mg/ml)
Host Rabbit
Clonality Polyclonal

NEK1 Antibody AbVantage™ Pack - A311-602A from Bethyl Labs

Prices $472.00
Sizes 1 pack
Host Rabbit
Clonality Polyclonal
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