NEK1

Gene Symbol	NEK1
Entrez Gene	4750
Alt Symbol	NY-REN-55, SRPS2, SRPS2A, SRTD6
Species	Human
Gene Type	protein-coding
Description	NIMA-related kinase 1
Other Description	NIMA (never in mitosis gene a)-related kinase 1|never in mitosis A-related kinase 1|nimA-related protein kinase 1|protein-serine/threonine kinase|renal carcinoma antigen NY-REN-55|serine/threonine-protein kinase Nek1
Swissprots	Q5H9T1 Q9Y594 Q05DG5 G5E9Z3 Q96PY6 Q96SS2 Q9H6P7 Q6PIB8 Q14CB7
Accessions	EAX04787 EAX04788 EAX04789 EAX04790 EAX04791 Q96PY6 AB067488 BAB67794 AF155113 AAD42879 AI984346 AK025658 BAB15207 AK027580 BAB55209 AL050385 CAI46225 BC015147 AAH15147 BC037790 AAH37790 BC068201 BC114491 AAI14492 CD358162 CR933642 CAI45943 CR936672 DA697159 Z25431 CAA80918 XM_006714228 XP_006714291 XM_011532003 XP_011530305 XM_011532004 XP_011530306 XM_011532005 XP_011530307 NM_001199397 NP_001186326 NM_001199398 NP_001186327 NM_001199399 NP_001186328 NM_001199400 NP_001186329 NM_012224 NP_036356
Function	Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Implicated in the control of meiosis (By similarity). Involved in cilium assembly. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death. {ECO:0000250, ECO:0000269|PubMed:20230784, ECO:0000269|PubMed:21211617}.
Subcellular Location	Nucleus {ECO:0000305|PubMed:21211617}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Associated with the pericentriolar material. Localizes to centrosome during interphase and mitosis (By similarity). {ECO:0000250}.
Tissue Specificity	High fetal expression in the brain and kidney. {ECO:0000269|PubMed:21211617}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human NEK1 protein fragment - ab133146 from Abcam Category Protein Prices $352.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Human NEK1 protein fragment - ab116949 from Abcam Category Protein Source Wheat germ Species Human

NEK1 Blocking Peptide - LS-E17621 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NEK1 Antibody Blocking Peptide - LS-E9471 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NEK1 Protein - H00004750-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NEK1 Peptide - P3068 from Novus Biologicals Category Peptide Species Human

NEK1-Antibody-C-term-Blocking-Peptide - BP8072b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NEK1 - H00004750-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NEK1 - H00004750-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NEK1 - P5609 from Acris Antibodies Category Protein Prices $1,010.00 Sizes 5 µg Species Human

NEK1 fusion protein - ag19904 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human NEK1 - NEK1-29277TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human NEK1 - NEK1-705H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Serine/threonine-protein kinase Nek1(NEK1) ,partial - CSB-YP836281HU CSB-EP836281HU CSB-BP836281HU CSB-MP836281HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NEK1 Recombinant Protein Antigen - NBP1-82884PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NEK1 Recombinant Protein Antigen - NBP1-82883PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NEK1 Peptide, Human - M34GP10286H from Creative Peptides Category Peptide Source Synthetic. Species Human

NEK1 fusion protein - Ag25970 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

NEK1 fusion protein - Ag25988 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET30a Species Human

Serine/threonine-protein kinase Nek1 (NEK1), partial, Recombinant Protein - MBS1459821 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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