MANF

Gene Symbol	MANF
Entrez Gene	7873
Alt Symbol	ARMET, ARP
Species	Human
Gene Type	protein-coding
Description	mesencephalic astrocyte-derived neurotrophic factor
Other Description	arginine-rich, mutated in early stage tumors
Swissprots	Q14CX4 Q86U67 P55145 Q96IS4
Accessions	CAH05640 EAW65138 P55145 AK292243 BAF84932 BC007282 AAH07282 BC033055 BC113588 AAI13589 BC113590 AAI13591 BE514267 BT007110 AAP35774 CN410909 CN410911 EU832655 ACE87746 EU832733 ACE87065 M83751 AAB08753 NM_006010 NP_006001
Function	Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. {ECO:0000250, ECO:0000269|PubMed:12794311, ECO:0000269|PubMed:18561914}.
Subcellular Location	Secreted {ECO:0000269|PubMed:12794311, ECO:0000269|PubMed:18561914}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MANF / ARMET ELISA Kit (Sandwich ELISA) - LS-F6514 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 15.6 pg/ml Range 15.6-1000 pg/ml

Human MANF ELISA Kit - abx152262 from Abbexa Category ELISA Kit Sensitivity 6.7 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Mesencephalic Astrocyte Derived Neurotrophic Factor, MANF, Human, ELISA Kit - E-EL-H0504 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF), Human, ELISA Kit - SEC300Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 6.4pg/mL Range 15.6-1,000pg/mL

Mesencephalic astrocyte-derived neurotrophic factor (ARMET), Human, ELISA Kit - CSB-EL002118HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Mesencephalic astrocyte-derived neurotrophic factor, MANF, Human, ELISA Kit - E9615h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t

Mesencephalic Astrocyte Derived Neurotrophic Factor, MANF, Rabbit, ELISA Kit - E-EL-RB0336 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Mesencephalic Astrocyte Derived Neurotrophic Factor, MANF, Chicken, ELISA Kit - E-EL-Ch1101 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Mesencephalic Astrocyte Derived Neurotrophic Factor, MANF, Porcine, ELISA Kit - E-EL-P1120 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Mesencephalic Astrocyte Derived Neurotrophic Factor, MANF, Sheep, ELISA Kit - E-EL-S0037 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Mesencephalic Astrocyte Derived Neurotrophic Factor, MANF, Guinea Pig, ELISA Kit - E-EL-GP0848 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Mesencephalic Astrocyte Derived Neurotrophic Factor, MANF, Monkey, ELISA Kit - E-EL-MK0357 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

MANF, ELISA Kit - MBS2511619 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625--1000pg/mL

MANF, ELISA Kit - MBS2511174 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469pg/mL Range 0.781-50pg/mL

MANF, ELISA Kit - MBS2507083 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625-1000pg/mL

MANF, ELISA Kit - MBS2500207 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.375pg/mL Range 0.625-40pg/mL

MANF, ELISA Kit - MBS2503797 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.469pg/mL Range 0.781-50pg/mL

MANF, ELISA Kit - MBS2502903 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

MANF, ELISA Kit - MBS2504444 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 9.375pg/mL Range 15.625-1000pg/mL

Human MANF(Mesencephalic Astrocyte Derived Neurotrophic Factor) ELISA Kit - E-EL-H0504 from Elabscience Category ELISA Kit Sensitivity 9.38 pg/mL Range 15.63—1000 pg/mL

Human MANF (Mesencephalic Astrocyte Derived Neurotrophic Factor) CLIA Kit - E-CL-H0408 from Elabscience Category CLIA Kit Sensitivity 7.50 pg/mL Range Average Recovery (%)

arginine-rich, mutated in early stage tumors, ELISA Kit - MBS706892 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of rat ARMET is typically less than 0.078 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.312 ng/ml -20 ng/ml.

arginine-rich, mutated in early stage tumors, ELISA Kit - MBS913619 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human ARMET is typically less than 1.56 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 6.25 ng/ml-400 ng/ml.

Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF), ELISA Kit - MBS9309072 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mesencephalic Astrocyte Derived Neurotrophic Factor (MANF), ELISA Kit - MBS2019025 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 6.7pg/mL. Range 15.63-1000pg/mL

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