MANF

Gene Symbol MANF
Entrez Gene 7873
Alt Symbol ARMET, ARP
Species Human
Gene Type protein-coding
Description mesencephalic astrocyte-derived neurotrophic factor
Other Description arginine-rich, mutated in early stage tumors
Swissprots Q14CX4 Q86U67 P55145 Q96IS4
Accessions CAH05640 EAW65138 P55145 AK292243 BAF84932 BC007282 AAH07282 BC033055 BC113588 AAI13589 BC113590 AAI13591 BE514267 BT007110 AAP35774 CN410909 CN410911 EU832655 ACE87746 EU832733 ACE87065 M83751 AAB08753 NM_006010 NP_006001
Function Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. {ECO:0000250, ECO:0000269|PubMed:12794311, ECO:0000269|PubMed:18561914}.
Subcellular Location Secreted {ECO:0000269|PubMed:12794311, ECO:0000269|PubMed:18561914}.

ARP (C-19) - sc-34560 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ARP (C-19): sc-34560. Western blot analysis of ARP expression in C32 whole cell lysate.

ARP (I-16) - sc-34561 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ARP (L-18) - sc-34562 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ARP (P-13) - sc-34563 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ARP (P-13): sc-34563. Western blot analysis of ARP expression in non-transfected: sc-117752 (A) and human ARP transfected: sc-373148 (B) 293T whole cell lysates.

ARP (H-108) - sc-366216 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-ARMET antibody - ab67271 from Abcam

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-ARMET antibody (ab67271) at 1 µg/mlLane 2 : Anti-ARMET antibody (ab67271) at 2 µg/mlLane 1 : Mouse brain tissue lysateLane 2 : Mouse brain tissue lysateLysates/proteins at 15 µg per lane.SecondaryAnti rabbit secondary antibody

Anti-ARMET antibody - ab67203 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-ARMET antibody (ab67203) at 1 µg/mlLane 2 : Anti-ARMET antibody (ab67203) at 2 µg/mlLane 1 : rat brain tissue lysateLane 2 : rat brain tissue lysate

Anti-ARMET antibody - ab129602 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ARMET antibody (ab129602) at 1/100 dilution + 293 cell line lysates at 35 µgdeveloped using the ECL technique

Anti-ARMET antibody [1G12] - ab130736 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G12
IHC image of ARMET staining in Human normal hippocampus formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab130736, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-MANF / ARMET Antibody (C-Terminus) IHC-plus™ - LS-B2688 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MANF / ARMET antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2688 concentration 5 ug/ml.

Anti-MANF / ARMET Antibody (aa170-182) - LS-C126890 from LifeSpan Bioscience

Prices $560.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-MANF / ARMET Antibody (aa19-48, AP) - LS-C262496 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MANF / ARMET Antibody (aa19-48, APC) - LS-C262497 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MANF / ARMET Antibody (aa23-51) - LS-C163986 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MANF Antibody western blot of 293 cell line lysates (35 ug/lane). The MANF antibody detected the MANF protein (arrow).

Anti-MANF / ARMET Antibody (aa19-48, Biotin) - LS-C262498 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MANF / ARMET Antibody (aa62-73) - LS-C54537 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.3 ug/ml) staining of Human Pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-MANF / ARMET Antibody (aa19-48, Azide-free, HRP) - LS-C262500 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MANF / ARMET Antibody (aa19-48, FITC) - LS-C262499 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MANF / ARMET Antibody (aa28-182, Biotin) - LS-C298175 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MANF / ARMET Antibody (aa19-48, PE) - LS-C262501 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MANF / ARMET Antibody (aa28-182, FITC) - LS-C303207 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MANF / ARMET Antibody - LS-C306371 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-MANF / ARMET Antibody (clone 1D10) - LS-C198507 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D10
Detection limit for recombinant GST tagged ARMET is 0.03 ng/ml as a capture antibody.

Anti-MANF / ARMET Antibody (aa103-152) - LS-C135565 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MANF / ARMET antibody LS-C135565 Western blot of HCT15 cell lysate.

Anti-MANF / ARMET Antibody (aa19-48) - LS-C322813 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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