Gene Symbol | CCM2 |
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Entrez Gene | 83605 |
Alt Symbol | C7orf22, OSM, PP10187 |
Species | Human |
Gene Type | protein-coding |
Description | cerebral cavernous malformation 2 |
Other Description | cerebral cavernous malformations 2 protein|malcavernin |
Swissprots | Q71RE5 D3DVL4 B3KUV0 F5H0E1 A4D2L4 F5H551 Q9BSQ5 Q8TAT4 E9PDJ3 |
Accessions | CAH56307 EAL23746 EAW61058 EAW61059 EAW61060 EAW61061 EAW61062 EAW61063 EAW61064 EAW61065 EAW61066 Q9BSQ5 AF370392 AAQ15228 AI538498 AK025807 AK098005 BAG53562 AK124060 AK298671 BAH12842 AK303216 BAH13921 AK303534 BAH13982 BC004903 AAH04903 BC008859 AAH08859 BC016832 AAH16832 BC025958 AAH25958 BC063663 AAH63663 BX641167 DA420491 JF432160 ADZ15377 XM_006715785 XP_006715848 XM_006715786 XP_006715849 XM_011515561 XP_011513863 XM_011515562 XP_011513864 XM_011515563 XP_011513865 XM_011515564 XP_011513866 XR_428088 NM_001029835 NP_001025006 NM_001167934 NP_001161406 NM_001167935 NP_001161407 NM_031443 NP_113631 NR_030770 |
Function | Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3- dependent p38 activation induced by hyperosmotic shock (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Malcavernin (D-19) - sc-67675 from Santa Cruz Biotechnology
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Malcavernin (H-85) - sc-68412 from Santa Cruz Biotechnology
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Malcavernin (T-14) - sc-67677 from Santa Cruz Biotechnology
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Anti-CCM2 antibody - ab53557 from Abcam
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Anti-CCM2 antibody - ab129386 from Abcam
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Anti-CCM2 antibody - ab155660 from Abcam
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Anti-CCM2 antibody - ab88834 from Abcam
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Anti-CCM2 antibody - ab88835 from Abcam
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Anti-CCM2 antibody [2E4] - ab123930 from Abcam
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Anti-CCM2 / Malcavernin Antibody - LS-C306781 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody - LS-C309762 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody (aa44-56) - LS-C54627 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody (clone 3B7) - LS-C173232 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody (clone 2C10) - LS-C173241 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody (clone 1B9) - LS-C173266 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody (clone 1D1) - LS-C337469 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody (clone 5H4) - LS-C173267 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody (clone 4F5) - LS-C173243 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody (clone 2E4) - LS-C173242 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody (clone 1E8) - LS-C337464 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody (clone 5C3) - LS-C337470 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody (clone 2F9) - LS-C337467 from LifeSpan Bioscience
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Anti-CCM2 / Malcavernin Antibody (clone 1E9) - LS-C337468 from LifeSpan Bioscience
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CCM2 Antibody (1E9) - NBP2-01134 from Novus Biologicals
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CCM2 Antibody - NB100-53812 from Novus Biologicals
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