CCM2

Gene Symbol	CCM2
Entrez Gene	83605
Alt Symbol	C7orf22, OSM, PP10187
Species	Human
Gene Type	protein-coding
Description	cerebral cavernous malformation 2
Other Description	cerebral cavernous malformations 2 protein|malcavernin
Swissprots	Q71RE5 D3DVL4 B3KUV0 F5H0E1 A4D2L4 F5H551 Q9BSQ5 Q8TAT4 E9PDJ3
Accessions	CAH56307 EAL23746 EAW61058 EAW61059 EAW61060 EAW61061 EAW61062 EAW61063 EAW61064 EAW61065 EAW61066 Q9BSQ5 AF370392 AAQ15228 AI538498 AK025807 AK098005 BAG53562 AK124060 AK298671 BAH12842 AK303216 BAH13921 AK303534 BAH13982 BC004903 AAH04903 BC008859 AAH08859 BC016832 AAH16832 BC025958 AAH25958 BC063663 AAH63663 BX641167 DA420491 JF432160 ADZ15377 XM_006715785 XP_006715848 XM_006715786 XP_006715849 XM_011515561 XP_011513863 XM_011515562 XP_011513864 XM_011515563 XP_011513865 XM_011515564 XP_011513866 XR_428088 NM_001029835 NP_001025006 NM_001167934 NP_001161406 NM_001167935 NP_001161407 NM_031443 NP_113631 NR_030770
Function	Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3- dependent p38 activation induced by hyperosmotic shock (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Malcavernin CRISPR/Cas9 KO Plasmid (h) - sc-410177 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Malcavernin HDR Plasmid (h) - sc-410177-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Malcavernin Double Nickase Plasmid (h) - sc-410177-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Malcavernin Double Nickase Plasmid (h2) - sc-410177-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Malcavernin CRISPR Activation Plasmid (h) - sc-410177-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Malcavernin CRISPR Activation Plasmid (h2) - sc-410177-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Malcavernin Lentiviral Activation Particles (h) - sc-410177-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Malcavernin Lentiviral Activation Particles (h2) - sc-410177-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Malcavernin siRNA (h) - sc-62594 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Malcavernin shRNA Plasmid (h) - sc-62594-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Malcavernin shRNA (h) Lentiviral Particles - sc-62594-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Oncostatin M/OSM RNAi - H00005008-R01 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

CCM2 RNAi - H00083605-R01 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU117881 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU130331 from Sigma-Aldrich Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN5624 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5624 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03509 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr03509

CCM2 siRNA (Human) - CRJ3141 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CCM2 RNAi - H00083605-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

CCM2 - MBS8232430 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CCM2 (NM_031443.3) - SHH257745 from Creative biogene Category siRNA Species Reactivities Human

Human CCM2 siRNA - orb273642 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CCM2 shRNA Plasmid (Human) - CHJ3141 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CCM2 miRNA 3'UTR clone - MiUTR3H-09581 from Creative biogene Species Reactivities Human

Search more