CCM2

Gene Symbol	CCM2
Entrez Gene	83605
Alt Symbol	C7orf22, OSM, PP10187
Species	Human
Gene Type	protein-coding
Description	cerebral cavernous malformation 2
Other Description	cerebral cavernous malformations 2 protein|malcavernin
Swissprots	Q71RE5 D3DVL4 B3KUV0 F5H0E1 A4D2L4 F5H551 Q9BSQ5 Q8TAT4 E9PDJ3
Accessions	CAH56307 EAL23746 EAW61058 EAW61059 EAW61060 EAW61061 EAW61062 EAW61063 EAW61064 EAW61065 EAW61066 Q9BSQ5 AF370392 AAQ15228 AI538498 AK025807 AK098005 BAG53562 AK124060 AK298671 BAH12842 AK303216 BAH13921 AK303534 BAH13982 BC004903 AAH04903 BC008859 AAH08859 BC016832 AAH16832 BC025958 AAH25958 BC063663 AAH63663 BX641167 DA420491 JF432160 ADZ15377 XM_006715785 XP_006715848 XM_006715786 XP_006715849 XM_011515561 XP_011513863 XM_011515562 XP_011513864 XM_011515563 XP_011513865 XM_011515564 XP_011513866 XR_428088 NM_001029835 NP_001025006 NM_001167934 NP_001161406 NM_001167935 NP_001161407 NM_031443 NP_113631 NR_030770
Function	Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3- dependent p38 activation induced by hyperosmotic shock (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CCM2 full length protein - ab113197 from Abcam Category Protein Prices $188.00 Sizes 20 µg Source E. coli Species Human

Human CCM2 protein fragment - ab174451 from Abcam Category Protein Prices $301.00 Sizes 50 µg Source E. coli Species Human

CCM2 / Malcavernin Antibody Blocking Peptide - LS-E26205 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

OSM / Oncostatin M Antibody Blocking Peptide - LS-E3351 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Oncostatin M/OSM Protein - NBP2-35114 from Novus Biologicals Category Protein Prices $69.00, $169.00, $4,629.00 Sizes 2 µg, 10 µg, 1 mg Source E. coli Species Human

Recombinant Human Oncostatin M/OSM Protein - NBP2-35115 from Novus Biologicals Category Protein Prices $69.00, $169.00, $4,629.00 Sizes 2 µg, 10 µg, 1 mg Source E. coli Species Human

Recombinant Human Oncostatin M/OSM Protein - NBP2-35113 from Novus Biologicals Category Protein Prices $69.00, $169.00, $929.00, $4,629.00 Sizes 2 µg, 10 µg, 100 µg, 1 mg Source E. coli Species Human

CCM2 Recombinant Protein - H00083605-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CCM2 Partial Recombinant Protein - H00083605-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Oncostatin M/OSM Recombinant Protein - H00005008-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

Recombinant Human CCM2 Protein - NBP2-22769 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E.coli Species Human

Oncostatin M/OSM Recombinant Protein - P3660 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Oncostatin M/OSM Protein - NBP1-99849 from Novus Biologicals Category Protein Prices $190.00 Sizes 10 µg Source E. coli Species Human

Recombinant Human Oncostatin M/OSM Protein - NBP1-72369 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

CCM2-Antibody-C-term-Blocking-Peptide - BP18117b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CCM2-Antibody-N-term-Blocking-Peptide - BP6875a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Oncostatin M recombinant protein - GTX53896 from GeneTex Category Protein Prices $199.00 Sizes 10 μg Source E. Coli

CCM2 blocking peptide - GTX89245-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Human OSM protein (His Tag) - orb168978 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human OSM, 209 a.a protein - orb168973 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Human OSM protein - orb78525 from Biorbyt Category Protein Prices $255.00, $391.00, $519.00 Sizes 10 μg, 50 μg, 100 μg Species Human

Human Oncostatin-M protein - orb80095 from Biorbyt Category Protein Prices $221.00, $357.00, $901.00, $1,530.00 Sizes 2 μg, 10 μg, 100 μg, 250 μg Source E.coli

Human OSM protein - orb168972 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli

Mouse OSM protein - orb168979 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli

Human OSM protein - orb168977 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source HEK.

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