CCM2

Gene Symbol	CCM2
Entrez Gene	83605
Alt Symbol	C7orf22, OSM, PP10187
Species	Human
Gene Type	protein-coding
Description	cerebral cavernous malformation 2
Other Description	cerebral cavernous malformations 2 protein|malcavernin
Swissprots	Q71RE5 D3DVL4 B3KUV0 F5H0E1 A4D2L4 F5H551 Q9BSQ5 Q8TAT4 E9PDJ3
Accessions	CAH56307 EAL23746 EAW61058 EAW61059 EAW61060 EAW61061 EAW61062 EAW61063 EAW61064 EAW61065 EAW61066 Q9BSQ5 AF370392 AAQ15228 AI538498 AK025807 AK098005 BAG53562 AK124060 AK298671 BAH12842 AK303216 BAH13921 AK303534 BAH13982 BC004903 AAH04903 BC008859 AAH08859 BC016832 AAH16832 BC025958 AAH25958 BC063663 AAH63663 BX641167 DA420491 JF432160 ADZ15377 XM_006715785 XP_006715848 XM_006715786 XP_006715849 XM_011515561 XP_011513863 XM_011515562 XP_011513864 XM_011515563 XP_011513865 XM_011515564 XP_011513866 XR_428088 NM_001029835 NP_001025006 NM_001167934 NP_001161406 NM_001167935 NP_001161407 NM_031443 NP_113631 NR_030770
Function	Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3- dependent p38 activation induced by hyperosmotic shock (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

OSM/Oncostatin M BioAssay™ ELISA Kit, Human - 144000 from USBiological Life Science Category ELISA Kit Sensitivity < 10 pg/ml Range 15.6pg/ml-1000pg/ml

Oncostatin M (OSM), Human, ELISA Kit - SEA110Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 6.0pg/mL Range 15.6-1,000pg/mL

Oncostatin-M, OSM, Human, ELISA Kit - E0110h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

OSM/Oncostatin M, Human, ELISA Kit - PB-0478 from ARP American Research Products Category ELISA Kit Prices $418.00 Sizes 96 t Sensitivity < 10 pg/ml Range 15.6pg/ml-1000pg/ml

Human OSM ELISA Kit - HO0334 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human OSM ELISA Kit - HO0009 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine OSM ELISA Kit - AO0334 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

cerebral cavernous malformation 2, ELISA Kit - MBS9341746 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

OSM (Human) ELISA Kit - DEIA4017 from Creative Diagnostics Category ELISA Kit Sensitivity The minimum detectable dose of Oncostatin M is typically less than 1 pg/mL.

Human OSM(Oncostatin M) ELISA Kit - E-EL-H2247 from Elabscience Category ELISA Kit Sensitivity 9.38 pg/mL Range 15.63—1000 pg/mL

Human OSM (Oncostatin M) CLIA Kit - E-CL-H1327 from Elabscience Category CLIA Kit Sensitivity 4.69 pg/mL Range Average Recovery (%)

Porcine Oncostatin M ELISA - E07O0002 from BlueGene Biotech Category ELISA Kit

Human Oncostatin M ELISA - E01O0002 from BlueGene Biotech Category ELISA Kit Sensitivity 1.0 pg/mL

Human PTPN11(Protein Tyrosine Phosphatase, Non Receptor Type 11) ELISA Kit - E-EL-H2247 from Iwai North America Inc. Category ELISA Kit Prices $580.00 Sizes 1 kit Sensitivity 9.38 pg/mLpg/mL Range 15.63~1000 pg/mL

Human OSM (Oncostatin M) CLIA Kit - E-CL-H1327 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 9.375pg/mL Range 15.625-1000pg/mL

Oncostatin M (OSM), Human, ELISA Kit - DL-OSM-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 15.6-1,000 pg/mL

Human OSM/Oncostatin M ELISA Kit - EA100334 from Acris Antibodies Category ELISA Kit Prices $389.00 Sizes 1 kit Range 10

Human OSM ELISA Kit - orb96776 from Biorbyt Category ELISA Kit Prices $612.00 Sizes 96 well Sensitivity < 10pg/ml Range 15.6pg/ml-1000pg/ml

Human OSM ELISA Kit - orb366113 from Biorbyt Category ELISA Kit Prices $510.00, $578.00 Sizes 48 test, 96 test Range Detection Range: 15.625-1000pg/mL Detection low threshold: 6.0pg/mL

Human OSM ELISA Kit - abx574573 from Abbexa Category ELISA Kit Sensitivity 6.0 pg/ml Range 15.625 pg/ml - 1000 pg/ml

OSM - EKH0498 from Nordic BioSite Sensitivity 9.375pg/ml Range 15.625-1000pg/ml

Human CCM2 ELISA Kit - E007858 from Biobool Category ELISA Kit

Human OSM ELISA Kit - E027690 from Biobool Category ELISA Kit Sensitivity 1.0 pg/mL.

Human OSM ELISA Kit - EHO0009 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

Human OSM ELISA Kit - EHO0334 from ABclonal Category ELISA Kit Prices $495.00 Sizes 96 t

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