FIS1

Gene Symbol FIS1
Entrez Gene 51024
Alt Symbol CGI-135, TTC11
Species Human
Gene Type protein-coding
Description fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
Other Description FIS1 homolog|H_NH0132A01.6|TPR repeat protein 11|hFis1|mitochondrial fission 1 protein|tetratricopeptide repeat domain 11|tetratricopeptide repeat protein 11
Swissprots Q9BTP3 Q9Y3D6
Accessions AAP22366 EAW50212 EAW50213 EAW50214 Q9Y3D6 AF151893 AAD34130 AK310968 AK311665 BC003540 AAH03540 BC009428 AAH09428 BI836529 HQ448311 ADQ32791 NM_016068 NP_057152
Function Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin- related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission. {ECO:0000269|PubMed:12783892, ECO:0000269|PubMed:12861026, ECO:0000269|PubMed:14996942, ECO:0000269|PubMed:16107562, ECO:0000269|PubMed:16118244, ECO:0000269|PubMed:23283981, ECO:0000269|PubMed:23530241}.
Subcellular Location Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.

Fis1 CRISPR/Cas9 KO Plasmid (h) - sc-401007 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fis1 HDR Plasmid (h) - sc-401007-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fis1 Double Nickase Plasmid (h) - sc-401007-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fis1 Double Nickase Plasmid (h2) - sc-401007-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fis1 CRISPR Activation Plasmid (h) - sc-401007-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fis1 CRISPR Activation Plasmid (h2) - sc-401007-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fis1 Lentiviral Activation Particles (h) - sc-401007-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fis1 Lentiviral Activation Particles (h2) - sc-401007-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Fis1 siRNA (h) - sc-60643 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Fis1 shRNA Plasmid (h) - sc-60643-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Fis1 shRNA (h) Lentiviral Particles - sc-60643-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN8701 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8701 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01289 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01289

FIS1 siRNA (Human) - CRH9464 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TTC11 RNAi - H00051024-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

FIS1 - MBS826985 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FIS1 (NM_016068.2) - SHH295093 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human FIS1(NM_016068.2) - SHH060167 from Creative biogene

Category siRNA
Species Reactivities Human

FIS1 shRNA Plasmid (Human) - CHH9464 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FIS1 miRNA 3'UTR clone - MiUTR1H-03662 from Creative biogene

Species Reactivities Human
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