Gene Symbol | ANP32B |
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Entrez Gene | 10541 |
Alt Symbol | APRIL, PHAPI2, SSP29 |
Species | Human |
Gene Type | protein-coding |
Description | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B |
Other Description | acidic leucine-rich nuclear phosphoprotein 32 family member B|acidic protein rich in leucines|putative HLA-DR-associated protein I-2|silver-stainable protein SSP29 |
Swissprots | Q92688 P78458 B2R9C7 P78459 O00655 |
Accessions | EAW58864 EAW58865 Q92688 AK223454 BAD97174 AK313733 BAG36474 AW296974 BC013003 AAH13003 BC019658 AAH19658 BP395780 U70439 AAB37579 Y07569 CAA68855 Y07570 CAA68856 Y07969 CAA69265 NM_006401 NP_006392 |
Function | Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome. {ECO:0000250, ECO:0000269|PubMed:20538007}. |
Subcellular Location | Isoform 1: Nucleus. Note=Accumulates in the nuclei at the S phase. {ECO:0000250}. |
Tissue Specificity | Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta. {ECO:0000269|PubMed:9473664}. |
Human PHAPI2 / APRIL full length protein - ab133003 from Abcam
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Human PHAPI2 / APRIL peptide - ab23013 from Abcam
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PHAPI2 / APRIL peptide - ab6093 from Abcam
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PHAPI2 / APRIL peptide - ab6094 from Abcam
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ANP32B / APRIL Antibody Blocking Peptide - LS-E4643 from LifeSpan Bioscience
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ANP32B / APRIL Antibody Blocking Peptide - LS-E25514 from LifeSpan Bioscience
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ANP32B / APRIL Antibody Blocking Peptide - LS-E18737 from LifeSpan Bioscience
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Recombinant Human ANP32B Protein - H00010541-P01 from Novus Biologicals
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ANP32B-Antibody-N-term-Blocking-Peptide - BP17005a from Abgent, a WuXi AppTec company
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ANP32B peptide - GTX26093 from GeneTex
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ANP32B peptide - GTX26094 from GeneTex
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ANP32B blocking peptide - GTX89831-PEP from GeneTex
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ANP32B Blocking Peptide - 33R-3427 from Fitzgerald
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TNFSF13 protein (T7 tag) - 80R-3735 from Fitzgerald
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PHAPI2 / APRIL Peptide - AC21-0342-P from Abcore
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ANP32B - H00010541-P01-10 from Acris Antibodies
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ANP32B - H00010541-P01-25 from Acris Antibodies
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APRIL, Recombinant Human - 213-10020-1 from RayBiotech
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Recombinant Human APRIL - 213-10020-2 from RayBiotech
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APRIL Peptide - 45-272P from ProSci
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ANP32B fusion protein - Ag1274 from Proteintech Group
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ANP32B fusion protein - ag18038 from Proteintech Group
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Recombinant Human ANP32B, GST-tagged - ANP32B-9686H from Creative Biomart
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Recombinant Human APRIL (TNFSF13) - APRIL-33H from Creative Biomart
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Recombinant Human APRIL (Carrier-free) - 21-8124 from Tonbo Biosciences
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