Gene Symbol | ANP32B |
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Entrez Gene | 10541 |
Alt Symbol | APRIL, PHAPI2, SSP29 |
Species | Human |
Gene Type | protein-coding |
Description | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B |
Other Description | acidic leucine-rich nuclear phosphoprotein 32 family member B|acidic protein rich in leucines|putative HLA-DR-associated protein I-2|silver-stainable protein SSP29 |
Swissprots | Q92688 P78458 B2R9C7 P78459 O00655 |
Accessions | EAW58864 EAW58865 Q92688 AK223454 BAD97174 AK313733 BAG36474 AW296974 BC013003 AAH13003 BC019658 AAH19658 BP395780 U70439 AAB37579 Y07569 CAA68855 Y07570 CAA68856 Y07969 CAA69265 NM_006401 NP_006392 |
Function | Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome. {ECO:0000250, ECO:0000269|PubMed:20538007}. |
Subcellular Location | Isoform 1: Nucleus. Note=Accumulates in the nuclei at the S phase. {ECO:0000250}. |
Tissue Specificity | Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta. {ECO:0000269|PubMed:9473664}. |
ANP32A/B (A-2) - sc-374552 from Santa Cruz Biotechnology
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ANP32A/B (H-163) - sc-292113 from Santa Cruz Biotechnology
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ANP32B (G-12) - sc-68219 from Santa Cruz Biotechnology
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Anti-PHAP antibody - ab5987 from Abcam
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Anti-PHAP antibody - ab5989 from Abcam
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Anti-PHAP antibody - ab19281 from Abcam
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Anti-PHAPI2 / APRIL antibody - ab168608 from Abcam
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Anti-PHAPI2 / APRIL antibody - ab130499 from Abcam
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Anti-PHAPI2 / APRIL antibody [EPR14588] - ab200836 from Abcam
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Anti-PHAPI2 / APRIL antibody [EPR14589] - ab184565 from Abcam
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Anti-ANP32B Antibody (aa17-45, AP) - LS-C251394 from LifeSpan Bioscience
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Anti-ANP32B Antibody (aa17-45, Biotin) - LS-C251397 from LifeSpan Bioscience
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Anti-ANP32B Antibody (aa17-45, APC) - LS-C251396 from LifeSpan Bioscience
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Anti-ANP32B Antibody (aa1-50) - LS-C119687 from LifeSpan Bioscience
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Anti-ANP32B Antibody (aa17-45) - LS-C156366 from LifeSpan Bioscience
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Anti-ANP32B Antibody (aa239-251) IHC-plus⢠- LS-B9185 from LifeSpan Bioscience
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Anti-ANP32B Antibody (aa17-45, FITC) - LS-C251398 from LifeSpan Bioscience
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Anti-ANP32B Antibody (aa17-45, Azide-free, HRP) - LS-C251399 from LifeSpan Bioscience
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Anti-ANP32B Antibody (aa16-45) - LS-C319493 from LifeSpan Bioscience
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Anti-ANP32B Antibody (aa17-45, PE) - LS-C251401 from LifeSpan Bioscience
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Anti-ANP32B Antibody (aa36-85) - LS-C102414 from LifeSpan Bioscience
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Anti-ANP32B Antibody (aa37-86) - LS-C200127 from LifeSpan Bioscience
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Anti-ANP32B Antibody (C-Terminus) - LS-C345649 from LifeSpan Bioscience
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APRIL/TNFSF13 Antibody (Aprily-8) - NBP1-97587 from Novus Biologicals
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APRIL/TNFSF13 Antibody [Unconjugated] - AF884 from Novus Biologicals
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