RAP1B

Gene Symbol RAP1B
Entrez Gene 5908
Alt Symbol K-REV, RAL1B
Species Human
Gene Type protein-coding
Description RAP1B, member of RAS oncogene family
Other Description GTP-binding protein smg p21B|RAS-related protein RAP1B|Ras family small GTP binding protein RAP1B|ras-related protein Rap-1b|small GTP binding protein
Swissprots Q502X3 B4DW74 Q6DCA1 B4DW94 Q6LES0 P61224 B2R5Z2 Q5TZR4 B4DQI8
Accessions ABQ52130 CAA00805 EAW97189 EAW97190 EAW97191 EAW97192 EAW97193 P61224 AA809981 AB062128 BAB93460 AF279894 AAK07551 AF493913 AAM12627 AJ420497 AK127392 AK298818 BAG60950 AK301401 BAG62936 AK301428 BAG62956 AK311559 AK312371 BAG35289 AK316447 BAH14818 AK316543 BAH14914 AL080212 CAB45777 AM393243 CAL38121 BC000176 AAH00176 BC078173 AAH78173 BC095467 AAH95467 BG717530 BT020093 AAV38896 CR407689 CAG28617 CX868584 DB448914 DQ583925 X08004 CAB46488 NM_001010942 NP_001010942 NM_001251917 NP_001238846 NM_001251918 NP_001238847 NM_001251921 NP_001238850 NM_001251922 NP_001238851 NM_015646 NP_056461
Function GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function. {ECO:0000269|PubMed:18660803, ECO:0000269|PubMed:20332120, ECO:0000269|PubMed:21840392}.
Subcellular Location Cell membrane. Cytoplasm, cytosol. Cell junction. Note=May shuttle between plasma membrane and cytosol. Presence of KRIT1 and CDH5 is required for its localization to the cell junction.
Top Pathways Rap1 signaling pathway, Focal adhesion, cAMP signaling pathway, Pancreatic secretion, Chemokine signaling pathway

RAP1B-Over-expression-Lysate - LY14344a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag RAP1B (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RAP1B gene.

RAP1B 293 Cell Lysate - 402150 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

RAP1B Overexpression Lysate (Native) - NBL1-15147 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: RAP1B Overexpression Lysate (Adult Normal) [NBL1-15147] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RAP1B.

RAP1B Overexpression Lysate (Native) - NBP2-08773 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: RAP1B Overexpression Lysate (Adult Normal) [NBP2-08773] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RAP1B.

RAP1B Overexpression Lysate (Native) - NBP2-09134 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: RAP1B Overexpression Lysate (Adult Normal) [NBP2-09134] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RAP1B.

Rab 1B (h): 293 Lysate - sc-110523 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

RAP1B Over-expression Lysate Product - GWB-6AC647 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Panoply™ Human RAP1B Knockdown Stable Cell Line - CSC-DC012960 from Creative biogene

Category Cell Line
Species Human
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