RAP1B

Gene Symbol	RAP1B
Entrez Gene	5908
Alt Symbol	K-REV, RAL1B
Species	Human
Gene Type	protein-coding
Description	RAP1B, member of RAS oncogene family
Other Description	GTP-binding protein smg p21B|RAS-related protein RAP1B|Ras family small GTP binding protein RAP1B|ras-related protein Rap-1b|small GTP binding protein
Swissprots	Q502X3 B4DW74 Q6DCA1 B4DW94 Q6LES0 P61224 B2R5Z2 Q5TZR4 B4DQI8
Accessions	ABQ52130 CAA00805 EAW97189 EAW97190 EAW97191 EAW97192 EAW97193 P61224 AA809981 AB062128 BAB93460 AF279894 AAK07551 AF493913 AAM12627 AJ420497 AK127392 AK298818 BAG60950 AK301401 BAG62936 AK301428 BAG62956 AK311559 AK312371 BAG35289 AK316447 BAH14818 AK316543 BAH14914 AL080212 CAB45777 AM393243 CAL38121 BC000176 AAH00176 BC078173 AAH78173 BC095467 AAH95467 BG717530 BT020093 AAV38896 CR407689 CAG28617 CX868584 DB448914 DQ583925 X08004 CAB46488 NM_001010942 NP_001010942 NM_001251917 NP_001238846 NM_001251918 NP_001238847 NM_001251921 NP_001238850 NM_001251922 NP_001238851 NM_015646 NP_056461
Function	GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function. {ECO:0000269|PubMed:18660803, ECO:0000269|PubMed:20332120, ECO:0000269|PubMed:21840392}.
Subcellular Location	Cell membrane. Cytoplasm, cytosol. Cell junction. Note=May shuttle between plasma membrane and cytosol. Presence of KRIT1 and CDH5 is required for its localization to the cell junction.
Top Pathways	Rap1 signaling pathway, Focal adhesion, cAMP signaling pathway, Pancreatic secretion, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RAP1B full length protein - ab103049 from Abcam Category Protein Source E. coli Species Human

Human RAP1B full length protein - ab176624 from Abcam Category Protein Source E. coli Species Human

Human Rap1B G12V full length protein - ab176634 from Abcam Category Protein Source E. coli Species Human

RAP1B Antibody Blocking Peptide - LS-E3649 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAP1B Antibody Blocking Peptide - LS-E20360 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RAP1B Recombinant Protein - H00005908-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

RAP1B Recombinant Protein - H00005908-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

RAP1B Partial Recombinant Protein - H00005908-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

Recombinant Human RAP1B Protein - NBP1-50971 from Novus Biologicals Category Protein Prices $349.00, $969.00 Sizes 50 µg, 250 µg Source E.coli Species Human

RAP1B-Antibody-C-term-Blocking-Peptide - BP14852b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RAP1B Protein (OPPA00055) - OPPA00055 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source Escherichia Coli.

Human RAP1B protein - orb169163 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

RAP1B Blocking Peptide - 33R-6359 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

RAP1B (1-181, His-tag) - AR09831PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 250 µg Source E. coli Species Human

RAP1B (1-181, His-tag) - AR09831PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 50 µg Source E. coli Species Human

RAP1B - H00005908-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RAP1B - H00005908-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RAP1B - H00005908-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

RAP1B - H00005908-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

RAP1B - H00005908-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

RAP1B - H00005908-Q01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

RAP1B - H00005908-Q01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Source in vitro transl. Species Human

RAP1B - H00005908-Q01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Source in vitro transl. Species Human

RAP1B, 1-181aa, Human, His tag, E.coli - 01-1858-1B from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

RAP1B fusion protein - Ag1282 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

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