KAT2A

Gene Symbol	KAT2A
Entrez Gene	2648
Alt Symbol	GCN5, GCN5L2, PCAF-b, hGCN5
Species	Human
Gene Type	protein-coding
Description	K(lysine) acetyltransferase 2A
Other Description	GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2|General control of amino acid synthesis, yeast, homolog-like 2|STAF97|general control of amino acid synthesis protein 5-like 2|histone acetyltransferase GCN5|histone acetyltransferase KAT2A|hsGCN5|lysine acetyltransferase 2A
Swissprots	Q9UCW1 Q8N1A2 Q92830
Accessions	AAC50641 EAW60801 EAW60802 EAW60803 Q92830 AF029777 AAC39769 BC032743 AAH32743 BC039907 AAH39907 BC105977 AAI05978 DB497139 XM_006721817 XP_006721880 XM_006721818 XP_006721881 NM_021078 NP_066564
Function	Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. {ECO:0000269|PubMed:19103755}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:11564863}.
Tissue Specificity	Expressed in all tissues tested, with most abundant expression in ovary.
Top Pathways	Notch signaling pathway, HTLV-I infection, Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human KAT2A / GCN5 protein fragment - ab198084 from Abcam Category Protein Prices $837.00 Sizes 50 µg Source Baculovirus infected sf9 cells Species Human

Human KAT2A / GCN5 full length protein - ab111648 from Abcam Category Protein Source E. coli Species Human

Human KAT2A / GCN5 protein fragment - ab198113 from Abcam Category Protein Source E. coli Species Human

KAT2A / GCN5 Antibody Blocking Peptide - LS-E498 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KAT2A / GCN5 Antibody Blocking Peptide - LS-E1490 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KAT2A / GCN5 Antibody Blocking Peptide - LS-E2177 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KAT2A/GCN5 Partial Recombinant Protein - H00002648-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human KAT2A/GCN5 Protein - NBP1-72426 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

KAT2A/GCN5 Peptide - P0197 from Novus Biologicals Category Peptide Species Human

KAT2A/GCN5 Peptide - P0196 from Novus Biologicals Category Peptide Species Human

KAT2A/GCN5 Peptide - P0195 from Novus Biologicals Category Peptide Species Human

KAT2A/GCN5 Recombinant Protein - P3938 from Novus Biologicals Category Protein Prices $549.00 Sizes 100 µg Species Human

GCN5-Antibody-N-term-Blocking-Peptide - BP1078d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GCN5-GCN5L2-Antibody-C-term-Blocking-peptide - BP1078b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GCN5-GCN5L2-Antibody-N-term-Blocking-peptide - BP1078a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

hGCN5-Antibody-C-term-Blocking-peptide - BP12198b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KAT2A-Antibody-C-term-Blocking-peptide - BP13089b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GCN5 blocking peptide - GTX15966-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse

Human KAT2A protein - orb168686 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

GCN5L2 protein (His tag) - 80R-1942 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

GCN5 Blocking Peptide - abx062123 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken

KAT2A / GCN5L2 (411-837, His-tag) - AR39124PU-L from Acris Antibodies Category Protein Prices $785.00 Sizes 500 µg Source E. coli Species Human

KAT2A / GCN5L2 (411-837, His-tag) - AR39124PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

KAT2A / GCN5L2 - H00002648-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

KAT2A / GCN5L2 - H00002648-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

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