KAT2A

Gene Symbol KAT2A
Entrez Gene 2648
Alt Symbol GCN5, GCN5L2, PCAF-b, hGCN5
Species Human
Gene Type protein-coding
Description K(lysine) acetyltransferase 2A
Other Description GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2|General control of amino acid synthesis, yeast, homolog-like 2|STAF97|general control of amino acid synthesis protein 5-like 2|histone acetyltransferase GCN5|histone acetyltransferase KAT2A|hsGCN5|lysine acetyltransferase 2A
Swissprots Q9UCW1 Q8N1A2 Q92830
Accessions AAC50641 EAW60801 EAW60802 EAW60803 Q92830 AF029777 AAC39769 BC032743 AAH32743 BC039907 AAH39907 BC105977 AAI05978 DB497139 XM_006721817 XP_006721880 XM_006721818 XP_006721881 NM_021078 NP_066564
Function Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. {ECO:0000269|PubMed:19103755}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11564863}.
Tissue Specificity Expressed in all tissues tested, with most abundant expression in ovary.
Top Pathways Notch signaling pathway, HTLV-I infection, Viral carcinogenesis

GCN5 CRISPR/Cas9 KO Plasmid (h) - sc-400767 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCN5 HDR Plasmid (h) - sc-400767-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCN5 Double Nickase Plasmid (h) - sc-400767-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCN5 Double Nickase Plasmid (h2) - sc-400767-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCN5 CRISPR Activation Plasmid (h) - sc-400767-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCN5 CRISPR Activation Plasmid (h2) - sc-400767-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCN5 Lentiviral Activation Particles (h) - sc-400767-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCN5 Lentiviral Activation Particles (h2) - sc-400767-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GCN5 siRNA (h) - sc-37946 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GCN5 shRNA Plasmid (h) - sc-37946-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GCN5 shRNA (h) Lentiviral Particles - sc-37946-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

KAT2A/GCN5 RNAi - H00002648-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU142761 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10895 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10895 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03965 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03965

KAT2A siRNA (Human) - CRH1762 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KAT2A, siRNA - MBS8214359 from MyBioSource

Category siRNA
Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KAT2A (NM_021078.2) - SHH322415 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human GCN5L2(NM_021078.2) - SHH080219 from Creative biogene

Category siRNA
Species Reactivities Human

Human KAT2A siRNA - orb262264 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KAT2A shRNA Plasmid (Human) - CHH1762 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KAT2A miRNA 3'UTR clone - MiUTR1H-03989 from Creative biogene

Species Reactivities Human
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