Gene Symbol | TACR1 |
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Entrez Gene | 6869 |
Alt Symbol | NK1R, NKIR, SPR, TAC1R |
Species | Human |
Gene Type | protein-coding |
Description | tachykinin receptor 1 |
Other Description | NK-1 receptor|NK-1R|substance-P receptor|tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor) |
Swissprots | P25103 A8K150 |
Accessions | AAY14950 AAY15031 CAA46292 EAW99595 EAW99596 P25103 AK289765 BAF82454 AW206679 AY462098 AAR23925 BC074911 AAH74911 BC074912 AAH74912 BC095528 AAH95528 DB203452 M74290 AAA60601 M76675 AAA59936 M81797 AAA59933 M84425 AAA36641 M84426 AAA36644 S62045 AAB20168 NM_001058 NP_001049 NM_015727 NP_056542 |
Function | This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, Measles, Neuroactive ligand-receptor interaction |
Human Neurokinin 1 Receptor full length protein - ab152721 from Abcam
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Human Neurokinin 1 Receptor protein fragment - ab152723 from Abcam
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Neurokinin 1 Receptor peptide - ab92810 from Abcam
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SPR Antibody Blocking Peptide - LS-E21817 from LifeSpan Bioscience
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SPR Antibody Blocking Peptide - LS-E10409 from LifeSpan Bioscience
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TACR1 / NK1R Antibody Blocking Peptide - LS-E2795 from LifeSpan Bioscience
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TACR1 / NK1R Antibody Blocking Peptide - LS-E26334 from LifeSpan Bioscience
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TACR1 / NK1R Antibody Blocking Peptide - LS-E28243 from LifeSpan Bioscience
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TACR1 / NK1R Antibody Blocking Peptide - LS-E28245 from LifeSpan Bioscience
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TACR1 / NK1R Antibody Blocking Peptide - LS-E28246 from LifeSpan Bioscience
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NK1R Blocking Peptide - NB300-101PEP from Novus Biologicals
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NK1R Blocking Peptide - NB300-119PEP from Novus Biologicals
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SPR Partial Recombinant Protein - H00006697-Q01 from Novus Biologicals
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Recombinant Human NK1R Protein - H00006869-P01 from Novus Biologicals
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Recombinant Human NK1R Protein - H00006869-Q01 from Novus Biologicals
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Recombinant Human NK1R Protein - H00006869-Q02 from Novus Biologicals
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SPR Recombinant Protein - H00006697-P01 from Novus Biologicals
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Recombinant Human SPR Protein - NBC1-21657 from Novus Biologicals
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Recombinant Human NK1R Protein - H00006869-G01 from Novus Biologicals
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TACR1-Antibody-Center-Blocking-peptide - BP13899c from Abgent, a WuXi AppTec company
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Neurokinin 1 Receptor blocking peptide - GTX89067-PEP from GeneTex
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Recombinant human Substance-P receptor (OPCA00829) - OPCA00829 from Aviva Systems Biology
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Human NK1R protein - orb245435 from Biorbyt
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Human Sepiapterin Reductase protein - orb90270 from Biorbyt
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Sepiapterin reductase protein (His tag) - 80R-1129 from Fitzgerald
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