TACR1

Gene Symbol	TACR1
Entrez Gene	6869
Alt Symbol	NK1R, NKIR, SPR, TAC1R
Species	Human
Gene Type	protein-coding
Description	tachykinin receptor 1
Other Description	NK-1 receptor|NK-1R|substance-P receptor|tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor)
Swissprots	P25103 A8K150
Accessions	AAY14950 AAY15031 CAA46292 EAW99595 EAW99596 P25103 AK289765 BAF82454 AW206679 AY462098 AAR23925 BC074911 AAH74911 BC074912 AAH74912 BC095528 AAH95528 DB203452 M74290 AAA60601 M76675 AAA59936 M81797 AAA59933 M84425 AAA36641 M84426 AAA36644 S62045 AAB20168 NM_001058 NP_001049 NM_015727 NP_056542
Function	This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Top Pathways	Calcium signaling pathway, Measles, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

NK-1R CRISPR/Cas9 KO Plasmid (h) - sc-401004 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-1R HDR Plasmid (h) - sc-401004-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-1R Double Nickase Plasmid (h) - sc-401004-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-1R Double Nickase Plasmid (h2) - sc-401004-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-1R CRISPR Activation Plasmid (h) - sc-401004-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-1R CRISPR Activation Plasmid (h2) - sc-401004-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-1R Lentiviral Activation Particles (h) - sc-401004-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-1R Lentiviral Activation Particles (h2) - sc-401004-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

NK-1R siRNA (h) - sc-36069 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NK-1R shRNA Plasmid (h) - sc-36069-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NK-1R shRNA (h) Lentiviral Particles - sc-36069-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

NK1R RNAi - H00006869-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

NK1R RNAi - H00006869-R03 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU053001 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20953 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20953 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02661 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr02661

TACR1 siRNA (Human) - CRH4698 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TACR1 - MBS8209817 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human TACR1 (NM_001058.3) - SHH422460 from Creative biogene Category siRNA Species Reactivities Human

Human TACR1 siRNA - orb265200 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TACR1 shRNA Plasmid (Human) - CHH4698 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

TACR1 miRNA 3'UTR clone - MiUTR3H-01534 from Creative biogene Species Reactivities Human

TACR1 miRNA 3'UTR clone - MiUTR4H-TG08729 from Creative biogene Species Reactivities Human

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